Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12060925 | 0.85 | NR1H2 (0.47) | NR1H2NR1H3TRPV4 | |
| SCHEMBL586534 | 0.83 | NR1H2 (0.50) | NR1H2NR1H3 | |
| SCHEMBL7636718 | 0.77 | IDO1 (0.41) | IDO1TRPV4 | |
| SCHEMBL10997473 | 0.73 | NR1H2 (0.44) | NR1H2NR1H3 | |
| SCHEMBL22551454 | 0.73 | IDO1 (0.32) | IDO1 | |
| SCHEMBL22551522 | 0.73 | IDO1 (0.32) | IDO1 | |
| Ethane SCHEMBL346861 | 0.71 | IDO1 (0.53) | IDO1TRPV4 | |
| SCHEMBL987122 | 0.71 | ACHE (0.53) | NR1H2NR1H3IDO1 | |
| SCHEMBL64710 | 0.71 | — | — | |
| SCHEMBL6036730 | 0.69 | IDO1 (0.33) | IDO1TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108884110-B | Sulfonium salt, photoacid generator, photocurable composition, and cured product thereof | 三亚普罗股份有限公司 | 2021-09-14 | — | — | CN | disclosed |
| US-9753188-B2 | Inorganic-organic hybrid material, optical material using the same, and inorganic-organic composite composition | NIPPON KASEI CHEMICAL COMPANY LIMITED (JP) | 2017-09-05 | — | — | US | disclosed |
| EP-2540734-B1 | Process and reagents for oligonucleotide synthesis and purification | ALNYLAM PHARMACEUTICALS INC (US) | 2016-03-30 | — | — | EP | disclosed |
| EP-2586826-B1 | INORGANIC-ORGANIC HYBRID MATERIAL, OPTICAL MATERIAL USING SAME, AND INORGANIC-ORGANIC COMPOSITE COMPOSITION | NIPPON KASEI CHEM (JP) | 2015-11-25 | — | — | EP | disclosed |
| CN-103038212-B | Process for preparation of 3-substituted-4-fluoropyrrolidine derivatives | KYORIN SEIYAKU KK | 2015-04-22 | — | — | CN | disclosed |
| US-20140316033-A1 | INORGANIC-ORGANIC HYBRID MATERIAL, OPTICAL MATERIAL USING THE SAME, AND INORGANIC-ORGANIC COMPOSITE COMPOSITION | NIPPON KASEI CHEMICAL COMPANY LIMITED (JP) | 2014-10-23 | — | — | US | disclosed |
| US-8815388-B2 | Inorganic-organic hybrid material, optical material using the same, and inorganic-organic composite composition | NIPPON KASEI CHEMICAL COMPANY LIMITED (JP) | 2014-08-26 | — | — | US | disclosed |
| US-8501965-B2 | Method for producing 3-substituted-4-fluoropyrrolidine derivative | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2013-08-06 | — | — | US | disclosed |
| US-20130116362-A1 | INORGANIC-ORGANIC HYBRID MATERIAL, OPTICAL MATERIAL USING THE SAME, AND INORGANIC-ORGANIC COMPOSITE COMPOSITION | MITSUBISHI CHEMICAL CORPORATION (JP) | 2013-05-09 | — | — | US | disclosed |
| EP-2586826-A1 | INORGANIC-ORGANIC HYBRID MATERIAL, OPTICAL MATERIAL USING SAME, AND INORGANIC-ORGANIC COMPOSITE COMPOSITION | Nippon Kasei Chemical Company Limited (JP) | 2013-05-01 | — | — | EP | disclosed |
| US-20130085282-A1 | METHOD FOR PRODUCING 3-SUBSTITUTED-4-FLUOROPYRROLIDINE DERIVATIVE | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2013-04-04 | — | — | US | disclosed |
| EP-2540734-A2 | Process and reagents for oligonucleotide synthesis and purification | Alnylam Pharmaceuticals, Inc. (US) | 2013-01-02 | — | — | EP | disclosed |
| US-8063198-B2 | Processes and reagents for desilylation of oligonucleotides | ALNYLAM PHARMACEUTICALS, INC. (US) | 2011-11-22 | — | — | US | disclosed |
| US-8058448-B2 | Processes and reagents for sulfurization of oligonucleotides | ALNYLAM PHARMACEUTICALS, INC. (US) | 2011-11-15 | — | — | US | disclosed |
| US-20110196145-A1 | PROCESS FOR DESILYLATION OF OLIGONUCLEOTIDES | ALNYLAM PHARMACEUTICALS, INC. (US) | 2011-08-11 | — | — | US | disclosed |
| US-20090187027-A1 | PROCESSES AND REAGENTS FOR SULFURIZATION OF OLIGONUCLEOTIDES | ALNYLAM PHARMACEUTICALS, INC. (US) | 2009-07-23 | — | — | US | disclosed |
| US-20090005549-A1 | Processes and Reagents for Desilylation of Oligonucleotides | ALNYLAM PHARMACEUTICALS, INC. (US) | 2009-01-01 | — | — | US | disclosed |
| EP-1737878-A2 | PROCESS AND REAGENTS FOR OLIGONUCLEOTIDE SYNTHESIS AND PURIFICATION | Alnylam Pharmaceuticals Inc. (US) | 2007-01-03 | — | — | EP | disclosed |
| US-20050267300-A1 | Processes and reagents for oligonucleotide synthesis and purification | ALNYLAM PHARMACEUTICALS | 2005-12-01 | — | — | US | disclosed |
| WO-2005097817-A2 | PROCESS AND REAGENTS FOR OLIGONUCLEOTIDE SYNTHESIS AND PURIFICATION | ALNYLAM PHARMACEUTICALS, INC. (US) | 2005-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110196145-A1 | PROCESS FOR DESILYLATION OF OLIGONUCLEOTIDES | ALKBH1, DIMT1, RNGTT | NR1H2 4876/4885NR1H3 4868/4885IDO1 522/4885 |
| US-20090005549-A1 | Processes and Reagents for Desilylation of Oligonucleotides | ALKBH1, DIMT1, RNGTT | NR1H2 4877/4885NR1H3 4871/4885IDO1 767/4885 |
| US-20050267300-A1 | Processes and reagents for oligonucleotide synthesis and purification | RNGTT, ALKBH1, MTAP | NR1H2 4884/4885NR1H3 4875/4885IDO1 796/4885 |
| US-20090187027-A1 | PROCESSES AND REAGENTS FOR SULFURIZATION OF OLIGONUCLEOTIDES | ALKBH1, RNGTT, MTAP | NR1H2 4884/4885NR1H3 4879/4885IDO1 765/4885 |
| US-20130085282-A1 | METHOD FOR PRODUCING 3-SUBSTITUTED-4-FLUOROPYRROLIDINE DERIVATIVE | NGLY1, SYNJ1, PFAS | NR1H2 4690/4885NR1H3 4644/4885IDO1 313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.