SCHEMBL132990

SCHEMBL132990

O=P(c1ccc2ccccc2c1)(c1ccc2ccccc2c1)c1ccc2ccccc2c1-c1c(P(=O)(c2ccc3ccccc3c2)c2ccc3ccccc3c2)ccc2ccccc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.38
WDR5 P61964 1/20 0.37
ALDH1A1 P00352 2/20 0.37
HSD17B10 Q99714 2/20 0.37
CYP2A6 P11509 1/20 0.37
TSHR P16473 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
HIF1A Q16665 1/20 0.36
CYP1B1 Q16678 1/20 0.36
CMA1 P23946 3/20 0.36
CTSG P08311 1/20 0.36
ACP3 P15309 1/20 0.36
DNMT1 P26358 1/20 0.36
CES1 P23141 2/20 0.36
GSTP1 P09211 1/20 0.35
GPR84 Q9NQS5 3/20 0.35
HPRT1 P00492 1/20 0.34
LMNA P02545 1/20 0.34
PTPN1 P18031 1/20 0.34
PAX8 Q06710 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11991070 0.95 WDR5 (0.38) MAPTWDR5ALDH1A1HSD17B10CYP2A6
SCHEMBL24380051 0.89 MAPT (0.31) MAPTWDR5CMA1CTSGACP3
SCHEMBL14339285 0.86 GPR84 (0.37) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL6932286 0.85
SCHEMBL132989 0.84 WDR5 (0.44) MAPTWDR5ALDH1A1HSD17B10CYP2A6
SCHEMBL29382484 0.84 WDR5 (0.44) MAPTWDR5ALDH1A1HSD17B10CYP2A6
SCHEMBL10710567 0.81 MAPT (0.39) MAPTWDR5ALDH1A1HSD17B10CYP2A6
SCHEMBL11991105 0.81 CES1 (0.45) MAPTWDR5ALDH1A1HSD17B10CYP2A6
SCHEMBL134309 0.81 LMNA (0.41) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL14339291 0.81 LMNA (0.41) ALDH1A1HSD17B10CYP2A6TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3005433-B1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2023-02-22 EP disclosed
US-11535640-B2 Metal complexes MERCK PATENT GMBH (DE) 2022-12-27 US disclosed
US-11145828-B2 Metal complexes MERCK PATENT GMBH (DE) 2021-10-12 US disclosed
US-11136343-B2 Binuclear metal complexes for use as emitters in organic electroluminescent devices MERCK PATENT GMBH (DE) 2021-10-05 US disclosed
EP-3658564-B1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2021-05-19 EP disclosed
EP-3507294-B1 BINUCLEAR AND TRINUCLEAR METAL COMPLEXES COMPOSED OF TWO INTER-LINKED TRIPODAL HEXADENTATE LIGANDS FOR USE IN ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-02-24 EP disclosed
EP-3117470-B1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2020-12-23 EP disclosed
EP-3526228-B1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2020-11-25 EP disclosed
EP-3515925-B1 BINUCLEAR METAL COMPLEXES FOR USE AS EMITTERS IN ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-10-21 EP disclosed
EP-3526226-B1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2020-07-22 EP disclosed
WO-2014194971-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2014-12-11 WO disclosed
US-20130168663-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2013-07-04 US disclosed
US-20130168663-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2013-07-04 US disclosed
US-20120056169-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH PATENTS & SCIENTIFIC INFORMATION (DE) 2012-03-08 US disclosed
US-20120056169-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH PATENTS & SCIENTIFIC INFORMATION (DE) 2012-03-08 US disclosed
EP-2251396-A2 Mixture of organic emission-capable semiconductors and matrix materials, use of same and electronic components containing same Merck Patent GmbH (DE) 2010-11-17 EP disclosed
US-7776455-B2 Organic electronic devices MERCK PATENT GMBH (DE) 2010-08-17 US disclosed
US-7776455-B2 Organic electronic devices MERCK PATENT GMBH (DE) 2010-08-17 US disclosed
US-20070170419-A1 Organic electronic devices MERCK PATENT GMBH (DE) 2007-07-26 US disclosed
US-20070170419-A1 Organic electronic devices MERCK PATENT GMBH (DE) 2007-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11145828-B2 Metal complexes AP1M1, AP2M1, AP3M1 MAPT 1250/4885WDR5 2307/4885ALDH1A1 4266/4885
US-11535640-B2 Metal complexes IMMT, MCU, SOD1 MAPT 1033/4885WDR5 3171/4885ALDH1A1 1473/4885
US-11136343-B2 Binuclear metal complexes for use as emitters in organic electroluminescent devices AP2M1, MCU, AP3M1 MAPT 1256/4885WDR5 2513/4885ALDH1A1 2989/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.