Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.73 |
| ▸ | RAB9A | P51151 | 10/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.73 |
| ▸ | CASP3 | P42574 | 1/20 | 0.73 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.58 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL668237 | 0.89 | KDM4E (0.62) | NPC1RAB9ASMN1; SMN2CASP3SENP7 | |
| SCHEMBL6858979 | 0.85 | ALDH1A1 (0.67) | NPC1RAB9ASMN1; SMN2CASP3SENP7 | |
| SCHEMBL29882235 | 0.85 | KDM4E (0.69) | NPC1RAB9ASMN1; SMN2CASP3SENP7 | |
| SCHEMBL7699682 | 0.84 | KMT2A (0.61) | NPC1RAB9ASMN1; SMN2CASP3SENP7 | |
| SCHEMBL1640023 | 0.81 | RAB9A (0.73) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL29394052 | 0.81 | RAB9A (0.73) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL27451660 | 0.81 | KMT2A (0.68) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL3121285 | 0.80 | MEN1 (0.60) | NPC1RAB9ASMN1; SMN2CASP3SENP7 | |
| SCHEMBL13516462 | 0.80 | MEN1 (1.00) | NPC1RAB9ASMN1; SMN2CASP3SENP7 | |
| SCHEMBL70117 | 0.79 | ALOX5 (0.59) | NPC1RAB9ASMN1; SMN2CASP3SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070161634-A1 | Compounds as CCR5 antagonists | SHANGHAI TARGET DRUG CO., LTD. (CN) | 2007-07-12 | — | — | US | claimed |
| EP-1760079-A1 | COMPOUNDS AS COR5 ANTAGONISTS | Shanghai Target Drug Co., Ltd. (CN) | 2007-03-07 | — | — | EP | claimed |
| EP-4622969-A1 | PESTICIDALLY ACTIVE CYCLIC AMINE COMPOUNDS | Syngenta Crop Protection AG (CH) | 2025-10-01 | — | — | EP | disclosed |
| CN-120118139-A | Catalpol derivative, synthesis process and application | 华东理工大学 | 2025-06-10 | — | — | CN | disclosed |
| WO-2025109114-A1 | NOVEL CARBOXAMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2025-05-30 | — | — | WO | disclosed |
| CN-119954787-A | Modulators of methyl-modified enzymes, compositions and uses thereof | 星座制药公司 | 2025-05-09 | — | — | CN | disclosed |
| WO-2025087761-A1 | PESTICIDALLY ACTIVE CYCLIC AMINE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2025-05-01 | — | — | WO | disclosed |
| CN-111989325-B | Modulators of methyl-modified enzymes, compositions and uses thereof | 星座制药公司 | 2025-02-25 | — | — | CN | disclosed |
| WO-2024110215-A1 | PESTICIDALLY ACTIVE CYCLIC AMINE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2024-05-30 | — | — | WO | disclosed |
| CN-114539249-B | Podophyllotoxin derivative tubulin inhibitor, and preparation method and medical application thereof | 中国药科大学 | 2024-01-26 | — | — | CN | disclosed |
| US-11584726-B2 | Amino alcohol derivative, pharmaceutical composition and application thereof | BEIJING FORELAND PHARMA CO., LTD. (CN) | 2023-02-21 | — | — | US | disclosed |
| US-5739336-A | SELECTIVE 5-HYDROXYTRYPTAMINE-2C RECEPTOR ANTAGONISTS | SYNTEX (U.S.A.) INC. (US) | 1998-04-14 | — | — | US | disclosed |
| WO-1997000872-A1 | 1,3,8-TRIAZA- AND 3,8-DIAZA-1-OXASPIRO(4,5)DECANE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 1997-01-09 | — | — | WO | disclosed |
| US-5489570-A | PRE- OR POST-EMERGENCE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1996-02-06 | — | — | US | disclosed |
| CN-1104212-A | Herbicides | RHONE POULENC AGRICULTURE (GB) | 1995-06-28 | — | — | CN | disclosed |
| EP-0636622-A1 | Isoxazole derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-02-01 | — | — | EP | disclosed |
| US-5238962-A | Administering an antidepressants | HOFFMANN-LA ROCHE INC. (US) | 1993-08-24 | — | — | US | disclosed |
| US-4803290-A | 1,2-AKKYLIDENE DIOXYBENZENE; FUNGICIDES | PCRI, INC. (US) | 1989-02-07 | — | — | US | disclosed |
| US-4058607-A | DIHALOVINYL DIALKYL PHOSPHATE, 1,3-BENZODIOXOLES | AIRWICK INDUSTRIES, INC. (US) | 1977-11-15 | — | — | US | disclosed |
| US-3932450-A | Intermediates in the preparation of imidazo(2,1-alpha)isoindoles | SANDOZ, INC. (US) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161634-A1 | Compounds as CCR5 antagonists | CCR5, CXCR3, CCL5 | NPC1 194/4885RAB9A 1642/4885SMN1; SMN2 4063/4885 |
| US-11584726-B2 | Amino alcohol derivative, pharmaceutical composition and application thereof | SSB, HLA-DRB1, LCP2 | NPC1 4456/4885RAB9A 4057/4885SMN1; SMN2 52/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.