Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RARA | P10276 | 2/20 | 0.33 |
| ▸ | RARB | P10826 | 2/20 | 0.33 |
| ▸ | RARG | P13631 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 2/20 | 0.32 |
| ▸ | GABRD | O14764 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19019685 | 0.80 | PRKAB2 (0.38) | KDM4EMEN1KMT2ARARARARB | |
| SCHEMBL16076561 | 0.76 | EIF4E (0.36) | TDP1RARARARBRARGPRKDC | |
| SCHEMBL16076572 | 0.73 | KMO (0.36) | TDP1MEN1KMT2AALPL | |
| SCHEMBL1918578 | 0.73 | KDM4E (0.40) | KDM4EMEN1KMT2AMAPTPOLB | |
| SCHEMBL2465852 | 0.71 | PPARA (0.38) | NUDT1TDP1MEN1KMT2AALPL | |
| SCHEMBL16076603 | 0.71 | CYP3A4 (0.38) | TDP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL20727047 | 0.71 | EIF4E (0.36) | TDP1RARARARBRARGPRKAB2 | |
| SCHEMBL16076583 | 0.70 | KMO (0.34) | TDP1MEN1KMT2A | |
| SCHEMBL2470387 | 0.70 | GRM2 (0.43) | TDP1 | |
| SCHEMBL2469705 | 0.70 | ALPL (0.47) | TDP1KDM4EMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8916498-B2 | Safening 6-(trisubstituted phenyl)-4-amino-2-pyridinecarboxylate herbicide injury on direct seeded and transplanted paddy rice | DOW AGROSCIENCES, LLC. (US) | 2014-12-23 | — | — | US | disclosed |
| US-8530383-B2 | Safening 6-(trisubstituted phenyl)-4-amino-2-pyridinecarboxylate herbicide injury on cereal crops | DOW AGROSCIENCES LLC (US) | 2013-09-10 | — | — | US | disclosed |
| US-20100130362-A1 | SAFENING 6-(TRISUBSTITUTED PHENYL)-4-AMINO-2-PYRIDINECARBOXYLATE HERBICIDE INJURY ON CEREAL CROPS | DOW AGROSCIENCES LLC (US) | 2010-05-27 | — | — | US | disclosed |
| US-20100130363-A1 | SAFENING COMPOSITION OF 6-(TRISUBSTITUTED PHENYL)-4-AMINO-2-PYRIDINECARBOXYLATE HERBICIDES AND CLOQUINTOCET-MEXYL FOR CEREAL CROPS | DOW AGROSCIENCES LLC (US) | 2010-05-27 | — | — | US | disclosed |
| US-20100130361-A1 | SAFENING 6-(TRISUBSTITUTED PHENYL)-4-AMINO-2-PYRIDINECARBOXYLATE HERBICIDE INJURY ON DIRECT SEEDED AND TRANSPLANTED PADDY RICE | DOW AGROSCIENCES LLC (US) | 2010-05-27 | — | — | US | disclosed |
| US-20090062121-A1 | SYNERGISTIC HERBICIDAL COMPOSITION CONTAINING CERTAIN PYRIDINE OR PYRIMIDINE CARBOXYLIC ACIDS AND CERTAIN CEREAL AND RICE HERBICIDES | DOW AGROSCIENCES LLC (US) | 2009-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130361-A1 | SAFENING 6-(TRISUBSTITUTED PHENYL)-4-AMINO-2-PYRIDINECARBOXYLATE HERBICIDE INJURY ON DIRECT SEEDED AND TRANSPLANTED PADDY RICE | DDT, CYP4F3, CYP3A43 | NUDT1 824/4885TDP1 3539/4885KDM4E 2509/4885 |
| US-20090062121-A1 | SYNERGISTIC HERBICIDAL COMPOSITION CONTAINING CERTAIN PYRIDINE OR PYRIMIDINE CARBOXYLIC ACIDS AND CERTAIN CEREAL AND RICE HERBICIDES | DHFR, DPYD, DDT | NUDT1 209/4885TDP1 1946/4885KDM4E 1949/4885 |
| US-20100130362-A1 | SAFENING 6-(TRISUBSTITUTED PHENYL)-4-AMINO-2-PYRIDINECARBOXYLATE HERBICIDE INJURY ON CEREAL CROPS | DDT, DBF4, DHFR | NUDT1 2652/4885TDP1 2469/4885KDM4E 2776/4885 |
| US-20100130363-A1 | SAFENING COMPOSITION OF 6-(TRISUBSTITUTED PHENYL)-4-AMINO-2-PYRIDINECARBOXYLATE HERBICIDES AND CLOQUINTOCET-MEXYL FOR CEREAL CROPS | PLPBP, MTX2, CIP2A | NUDT1 1110/4885TDP1 1370/4885KDM4E 1424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.