Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12991152 | 0.92 | MAPT (0.45) | KDM4EMAPTRXFP1LMNAPOLB | |
| SCHEMBL13127423 | 0.91 | MAPT (0.44) | KDM4EMAPTRXFP1LMNAPOLB | |
| SCHEMBL12036885 | 0.89 | KDM4E (0.42) | KDM4EMAPTRXFP1LMNAPOLB | |
| SCHEMBL12057407 | 0.82 | TSPO (0.43) | KDM4EMAPTLMNATDP1ALDH1A1 | |
| SCHEMBL12036827 | 0.81 | TSPO (0.42) | KDM4EMAPTLMNAPOLBL3MBTL1 | |
| SCHEMBL30557701 | 0.80 | KDM4E (0.57) | KDM4EMAPTLMNAPOLBL3MBTL1 | |
| SCHEMBL28912383 | 0.80 | KDM4E (0.57) | KDM4EMAPTLMNAPOLBL3MBTL1 | |
| SCHEMBL12991095 | 0.79 | LMNA (0.38) | KDM4EMAPTLMNAL3MBTL1NPSR1 | |
| SCHEMBL12991205 | 0.77 | MAPT (0.59) | KDM4EMAPTLMNAPOLBL3MBTL1 | |
| SCHEMBL439393 | 0.77 | RXFP1 (0.74) | KDM4EMAPTRXFP1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110281388-A1 | Cross-Linked Quantum Dots and Methods for Producing and Using the Same | HCF PARTNERS, LP (US) | 2011-11-17 | — | — | US | disclosed |
| US-20110245429-A1 | Cross Linked Organic Conductive Layer | GOUGH, NEIL (GB) | 2011-10-06 | — | — | US | disclosed |
| US-20110245429-A1 | Cross Linked Organic Conductive Layer | GOUGH, NEIL (GB) | 2011-10-06 | — | — | US | disclosed |
| US-20110245429-A1 | Cross Linked Organic Conductive Layer | GOUGH, NEIL (GB) | 2011-10-06 | — | — | US | disclosed |
| US-20100308754-A1 | Hole Transport Polymer for Use in Electronic Devices | HCF PARTNERS, LP (US) | 2010-12-09 | — | — | US | disclosed |
| US-20100308754-A1 | Hole Transport Polymer for Use in Electronic Devices | HCF PARTNERS, LP (US) | 2010-12-09 | — | — | US | disclosed |
| US-20100308754-A1 | Hole Transport Polymer for Use in Electronic Devices | HCF PARTNERS, LP (US) | 2010-12-09 | — | — | US | disclosed |
| CN-101903345-A | Be used in the hole transport polymer in the electron device | HCF PARTNERS LP | 2010-12-01 | — | — | CN | disclosed |
| EP-2215060-A1 | HOLE TRANSPORT POLYMER FOR USE IN ELECTRONIC DEVICES | Dynamic Organic Light, Inc. (US) | 2010-08-11 | — | — | EP | disclosed |
| WO-2010068205-A1 | CROSS LINKED ORGANIC CONDUCTIVE LAYER | HCF PARTNERS, L.P. (US) | 2010-06-17 | — | — | WO | disclosed |
| WO-2010068205-A1 | CROSS LINKED ORGANIC CONDUCTIVE LAYER | HCF PARTNERS, L.P. (US) | 2010-06-17 | — | — | WO | disclosed |
| WO-2009061314-A1 | HOLE TRANSPORT POLYMER FOR USE IN ELECTRONIC DEVICES | DYNAMIC ORGANIC LIGHT, INC. (US) | 2009-05-14 | — | — | WO | disclosed |
| WO-2009061314-A1 | HOLE TRANSPORT POLYMER FOR USE IN ELECTRONIC DEVICES | DYNAMIC ORGANIC LIGHT, INC. (US) | 2009-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110245429-A1 | Cross Linked Organic Conductive Layer | GJB2, GJA1, KCNH3 | KDM4E 864/4885MAPT 1700/4885RXFP1 4799/4885 |
| US-20110281388-A1 | Cross-Linked Quantum Dots and Methods for Producing and Using the Same | MTCL3, DUOX2, NQO2 | KDM4E 1968/4885MAPT 1266/4885RXFP1 3905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.