Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1332953 | 0.85 | TAS1R3 (0.42) | TAS1R3TAS1R1LMNATDP1MEN1 | |
| SCHEMBL8333245 | 0.82 | HPGD (0.49) | TAS1R3TAS1R1MAPTNPSR1CYP1A2 | |
| SCHEMBL77601 | 0.78 | MAPT (0.53) | MAPTGSK3BKDM4EALDH1A1HPGD | |
| SCHEMBL19450577 | 0.78 | TDP1 (0.44) | TAS1R3TAS1R1LMNATDP1MEN1 | |
| SCHEMBL11776380 | 0.78 | GLO1 (0.42) | TAS1R3TAS1R1LMNAMAPTGSK3B | |
| SCHEMBL28126890 | 0.77 | KMT2A (0.53) | LMNAMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL438314 | 0.76 | MEN1 (0.70) | LMNAMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL8328530 | 0.76 | LMNA (0.63) | TAS1R3TAS1R1LMNATDP1MEN1 | |
| SCHEMBL28841141 | 0.75 | KMT2A (0.51) | TAS1R3TAS1R1LMNATDP1MEN1 | |
| SCHEMBL8182437 | 0.75 | MEN1 (0.64) | LMNAMEN1KMT2AMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120128745-A1 | BENZYLIDENE MALONATES | BASF SE (DE) | 2012-05-24 | — | — | US | disclosed |
| US-20120128745-A1 | BENZYLIDENE MALONATES | BASF SE (DE) | 2012-05-24 | — | — | US | disclosed |
| WO-2010136360-A2 | BENZYLIDENE MALONATES | BASF SE (DE) | 2010-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120128745-A1 | BENZYLIDENE MALONATES | TERT, REL, MGMT | TAS1R3 773/4885TAS1R1 380/4885LMNA 2000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.