Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 7/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.70 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.63 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.63 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1334253 | 0.98 | KCNH2 (0.73) | LTA4HKCNH2TMEM97SIGMAR1HRH3 | |
| SCHEMBL13150797 | 0.89 | SIGMAR1 (0.72) | LTA4HKCNH2SIGMAR1HRH3 | |
| SCHEMBL1334161 | 0.89 | KCNH2 (0.66) | LTA4HKCNH2TMEM97SIGMAR1HRH3 | |
| SCHEMBL1334145 | 0.88 | SIGMAR1 (0.71) | LTA4HKCNH2SIGMAR1HRH3 | |
| Hydrochloric Acid SCHEMBL1334031 | 0.87 | SIGMAR1 (0.69) | LTA4HKCNH2SIGMAR1HRH3 | |
| SCHEMBL1332740 | 0.85 | L3MBTL1 (0.65) | LTA4HKCNH2 | |
| SCHEMBL1332021 | 0.85 | KCNH2 (0.64) | LTA4HKCNH2TMEM97SIGMAR1SLC6A3 | |
| SCHEMBL1334024 | 0.85 | LMNA (0.69) | LTA4HKCNH2TMEM97SIGMAR1 | |
| SCHEMBL1333781 | 0.85 | SIGMAR1 (0.78) | LTA4HKCNH2SIGMAR1HRH3 | |
| SCHEMBL1333955 | 0.85 | HRH3 (0.62) | LTA4HKCNH2TMEM97SIGMAR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100256162-A1 | Piperazine and Piperidine Derivatives | AGY THERAPEUTICS, INC. (US) | 2010-10-07 | — | — | US | claimed |
| US-20100137334-A1 | Piperidine and Piperazine Derivatives | SUN CONNIE L | 2010-06-03 | — | — | US | claimed |
| EP-1978959-A4 | PIPERIDINE AND PIPERAZINE DERIVATIVES | MS SCIENCE CORP (JP) | 2009-09-02 | — | — | EP | claimed |
| EP-1976525-A4 | PIPERIDINE AND PIPERAZINE DERIVATIVES | MS SCIENCE CORP (JP) | 2009-07-15 | — | — | EP | claimed |
| EP-1978959-A2 | PIPERIDINE AND PIPERAZINE DERIVATIVES | M's Science Corporation (JP) | 2008-10-15 | — | — | EP | claimed |
| EP-1976525-A2 | PIPERIDINE AND PIPERAZINE DERIVATIVES | M's Science Corporation (JP) | 2008-10-08 | — | — | EP | claimed |
| WO-2008096189-A2 | PIPERIDINE AND PIPERAZINE DERIVATIVES | M'S SCIENCE CORPORATION (JP) | 2008-08-14 | — | — | WO | claimed |
| WO-2007089462-A2 | PIPERIDINE AND PIPERAZINE DERIVATIVES | M'S SCIENCE CORPORATION (JP) | 2007-08-09 | — | — | WO | claimed |
| US-20130072497-A1 | N- SUBSTITUTED PIPERAZINES | DOW AGROSCIENCES LLC (US) | 2013-03-21 | — | — | US | disclosed |
| US-20130072497-A1 | N- SUBSTITUTED PIPERAZINES | DOW AGROSCIENCES LLC (US) | 2013-03-21 | — | — | US | disclosed |
| US-8338430-B2 | N-substituted piperazines | DOW AGROSCIENCES, LLC. (US) | 2012-12-25 | — | — | US | disclosed |
| US-8338430-B2 | N-substituted piperazines | DOW AGROSCIENCES, LLC. (US) | 2012-12-25 | — | — | US | disclosed |
| US-8183374-B2 | Piperidine and piperazine derivatives | M'S SCIENCE CORPORATION (JP) | 2012-05-22 | — | — | US | disclosed |
| US-8183374-B2 | Piperidine and piperazine derivatives | M'S SCIENCE CORPORATION (JP) | 2012-05-22 | — | — | US | disclosed |
| EP-1978959-A2 | PIPERIDINE AND PIPERAZINE DERIVATIVES | M's Science Corporation (JP) | 2008-10-15 | — | — | EP | disclosed |
| EP-1976525-A2 | PIPERIDINE AND PIPERAZINE DERIVATIVES | M's Science Corporation (JP) | 2008-10-08 | — | — | EP | disclosed |
| WO-2008096189-A2 | PIPERIDINE AND PIPERAZINE DERIVATIVES | M'S SCIENCE CORPORATION (JP) | 2008-08-14 | — | — | WO | disclosed |
| WO-2007089462-A2 | PIPERIDINE AND PIPERAZINE DERIVATIVES | M'S SCIENCE CORPORATION (JP) | 2007-08-09 | — | — | WO | disclosed |
| US-20070004750-A1 | N-substituted piperazines | CORTEVA AGRISCIENCE LLC | 2007-01-04 | — | — | US | disclosed |
| US-20070004750-A1 | N-substituted piperazines | CORTEVA AGRISCIENCE LLC | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004750-A1 | N-substituted piperazines | PRXL2A, CNPY2, CYP4X1 | LTA4H 3316/4885KCNH2 87/4885TMEM97 1579/4885 |
| US-20100137334-A1 | Piperidine and Piperazine Derivatives | SIGMAR1, OPRM1, OPRD1 | LTA4H 2934/4885KCNH2 332/4885TMEM97 8/4885 |
| US-20130072497-A1 | N- SUBSTITUTED PIPERAZINES | PRXL2A, CNPY2, CYP4X1 | LTA4H 3316/4885KCNH2 87/4885TMEM97 1579/4885 |
| US-20100256162-A1 | Piperazine and Piperidine Derivatives | SIGMAR1, OPRM1, OPRD1 | LTA4H 3616/4885KCNH2 360/4885TMEM97 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.