Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.44 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13348407 | 0.90 | FFAR1 (0.38) | ALDH1A1PARP10PARP14PTGER4PTGER2 | |
| SCHEMBL13312466 | 0.89 | ALDH1A1 (0.46) | ALDH1A1PARP10PARP14PTGER4PTGER2 | |
| SCHEMBL13348240 | 0.86 | PTGER2 (0.49) | ALDH1A1PTGER4PTGER2KMT2AMEN1 | |
| SCHEMBL13348170 | 0.84 | PTGER4 (0.39) | ALDH1A1PARP10PARP14PTGER4PTGER2 | |
| SCHEMBL13348138 | 0.81 | HPD (0.41) | ALDH1A1PTGER4PTGER2 | |
| SCHEMBL13348415 | 0.81 | TSHR (0.43) | ALDH1A1PARP10PARP14PTGER4PTGER2 | |
| SCHEMBL13348045 | 0.80 | DRD2 (0.39) | ALDH1A1PTGER4PTGER2KMT2AMEN1 | |
| SCHEMBL13312474 | 0.79 | FFAR1 (0.51) | DRD3 | |
| SCHEMBL13312467 | 0.78 | FFAR1 (0.43) | PTGER4PTGER2 | |
| SCHEMBL13348179 | 0.77 | PTGER4 (0.43) | ALDH1A1PTGER4PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | GPR119, GPR65, HCAR1 | ALDH1A1 1850/4885PARP10 2338/4885PARP14 3772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.