Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.70 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.66 |
| ▸ | ESR1 | P03372 | 4/20 | 0.66 |
| ▸ | APP | P05067 | 2/20 | 0.61 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.59 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.59 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL311766 | 0.85 | ALDH1A1 (0.66) | CYP1A1CYP1A2CYP1B1ESR2ESR1 | |
| SCHEMBL8934506 | 0.84 | TUBB4A (0.79) | CYP1A1CYP1A2CYP1B1APPCSNK2A2 | |
| SCHEMBL30269738 | 0.81 | CYP1A2 (0.67) | CYP1A1CYP1A2CYP1B1APPCSNK2A2 | |
| SCHEMBL10305796 | 0.81 | TERT (0.66) | CYP1A1CYP1A2CYP1B1ESR2ESR1 | |
| SCHEMBL30685309 | 0.80 | CYP1B1 (0.56) | CYP1A1CYP1A2CYP1B1ESR2ESR1 | |
| SCHEMBL3928011 | 0.80 | ESR1 (1.00) | CYP1A1CYP1A2CYP1B1ESR2ESR1 | |
| SCHEMBL10305783 | 0.80 | MEN1 (0.66) | CYP1A1CYP1A2CYP1B1APPCSNK2A2 | |
| SCHEMBL8934614 | 0.79 | KDM4E (0.74) | CYP1A1CYP1A2CYP1B1ESR2CSNK2A2 | |
| SCHEMBL2874033 | 0.78 | POLH (0.79) | CYP1A1CYP1A2CYP1B1ESR2ESR1 | |
| SCHEMBL10305800 | 0.77 | AKR1B1 (0.64) | CYP1A1CYP1A2CYP1B1ESR2CSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1600061-B1 | Oral and/or topical compositions | COGNIS IP MAN GMBH (DE) | 2010-05-12 | — | — | EP | disclosed |