SCHEMBL10305783

SCHEMBL10305783

COc1ccc(-c2cc(=O)c3cc(O)cc(O)c3o2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 7/20 0.66
▸ KMT2A Q03164 7/20 0.66
▸ MAPT P10636 6/20 0.66
▸ NPC1 O15118 4/20 0.66
▸ RAB9A P51151 4/20 0.66
▸ NFKB1 P19838 2/20 0.66
▸ NFKB2 Q00653 2/20 0.66
▸ RELA Q04206 2/20 0.66
▸ CSNK2A2 P19784 1/20 0.66
▸ RECQL P46063 1/20 0.66
▸ CSNK2B P67870 1/20 0.66
▸ CSNK2A1 P68400 1/20 0.66
▸ CYP3A4 P08684 7/20 0.64
▸ ALDH1A1 P00352 7/20 0.64
▸ TP53 P04637 6/20 0.64
▸ CYP2C9 P11712 4/20 0.64
▸ CYP2C19 P33261 4/20 0.64
▸ MAOB P27338 4/20 0.64
▸ CYP1A1 P04798 4/20 0.64
▸ CYP1A2 P05177 4/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10305796 0.86 TERT (0.66) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL10305800 0.81 AKR1B1 (0.64) MAPTCSNK2A2RECQLCSNK2BCSNK2A1
SCHEMBL6614508 0.81 TERT (0.73) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL6618581 0.80 TUBB4A (0.67) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL490928 0.80 MAPT (1.00) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL13355967 0.80 CYP1A1 (0.70) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL31675989 0.80 MAPT (1.00) MEN1KMT2AMAPTNPC1RAB9A
Acacetin SCHEMBL29387049 0.78 CYP1B1 (1.00) MEN1KMT2AMAPTNPC1RAB9A
Acacetin SCHEMBL107712 0.78 CYP1B1 (1.00) MEN1KMT2AMAPTNPC1RAB9A
Acacetin SCHEMBL28278297 0.77 CYP1B1 (0.97) MEN1KMT2AMAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8293315-B2 Process for the preparation of active substance concentrate COGNIS IP MANAGEMENT GMBH (DE) 2012-10-23 — — US disclosed
US-8293315-B2 Process for the preparation of active substance concentrate COGNIS IP MANAGEMENT GMBH (DE) 2012-10-23 — — US disclosed
EP-1738738-B1 Microcapsules COGNIS IP MAN GMBH (DE) 2012-07-11 — — EP disclosed
EP-2060251-B1 Method for manufacturing active agent concentrates COGNIS IP MAN GMBH (DE) 2011-03-23 — — EP disclosed
EP-1600061-B1 Oral and/or topical compositions COGNIS IP MAN GMBH (DE) 2010-05-12 — — EP disclosed
US-20100009063-A1 Process for the preparation of active substance concentrate COGNIS IP MANAGEMENT GMBH (DE) 2010-01-14 — — US disclosed
US-20100009063-A1 Process for the preparation of active substance concentrate COGNIS IP MANAGEMENT GMBH (DE) 2010-01-14 — — US disclosed
EP-2060251-A1 Method for manufacturing active agent concentrates Cognis IP Management GmbH (DE) 2009-05-20 — — EP disclosed
EP-1623757-B1 Microcapsules (XXXII) COGNIS IP MAN GMBH (DE) 2009-02-11 — — EP disclosed
US-20080268024-A1 Compositions for Oral and/or Topical Administration COGNIS IP MANAGEMENT GMBH (DE) 2008-10-30 — — US disclosed
US-20080268024-A1 Compositions for Oral and/or Topical Administration COGNIS IP MANAGEMENT GMBH (DE) 2008-10-30 — — US disclosed
US-20080220101-A1 COMPOSITIONS OF EXTRACTS OF ALOE FOR ORAL ADMINISTRATION COGNIS IP MANAGEMENT GMBH (DE) 2008-09-11 — — US disclosed
US-20080220101-A1 COMPOSITIONS OF EXTRACTS OF ALOE FOR ORAL ADMINISTRATION COGNIS IP MANAGEMENT GMBH (DE) 2008-09-11 — — US disclosed
EP-1967197-A1 Use of preparations, purifications and extracts of aloe Cognis IP Management GmbH (DE) 2008-09-10 — — EP disclosed
WO-2008046521-A1 PREPARATION FOR ORAL ADMINISTRATION (II) COGNIS IP MANAGEMENT GMBH (DE) 2008-04-24 — — WO disclosed
WO-2008028585-A2 COSMETIC AND/OR PHARMACEUTICAL PREPARATIONS CONTAINING HOODIA EXTRACTS COGNIS IP MANAGEMENT GMBH (DE) 2008-03-13 — — WO disclosed
WO-2008028584-A1 PREPARATIONS FOR ORAL ADMINISTRATION (I) COGNIS IP MANAGEMENT GMBH (DE) 2008-03-13 — — WO disclosed
WO-2007068390-A1 PRE-MIXES FOR PERSONAL AND HOME CARE COMPOSITIONS COGNIS IP MANAGEMENT GMBH (DE) 2007-06-21 — — WO disclosed
EP-1798279-A1 Pre-mixes for personal and home care compositions Cognis IP Management GmbH (DE) 2007-06-20 — — EP disclosed
EP-1738738-A1 Microcapsules Cognis IP Management GmbH (DE) 2007-01-03 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080268024-A1 Compositions for Oral and/or Topical Administration FABP2, FABP6, CUTA MEN1 2644/4885KMT2A 4465/4885MAPT 184/4885
US-20080220101-A1 COMPOSITIONS OF EXTRACTS OF ALOE FOR ORAL ADMINISTRATION LIPE, ALOX15, ALOX5 MEN1 1604/4885KMT2A 3788/4885MAPT 4750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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