SCHEMBL10305796

SCHEMBL10305796

O=c1cc(-c2ccc(O)cc2)oc2c(O)cc(O)cc12

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 1/20 0.66
▸ CSNK2A2 P19784 5/20 0.62
▸ CSNK2B P67870 5/20 0.62
▸ CSNK2A1 P68400 5/20 0.62
▸ MAPT P10636 5/20 0.62
▸ SMN1; SMN2 Q16637 4/20 0.62
▸ CYP3A4 P08684 4/20 0.62
▸ HPGD P15428 4/20 0.62
▸ NPC1 O15118 4/20 0.62
▸ IP6K2 Q9UHH9 3/20 0.62
▸ THRB P10828 3/20 0.62
▸ RAB9A P51151 3/20 0.62
▸ LMNA P02545 2/20 0.62
▸ TP53 P04637 2/20 0.62
▸ ALOX15 P16050 2/20 0.62
▸ CASP3 P42574 1/20 0.62
▸ SENP8 Q96LD8 1/20 0.62
▸ SENP7 Q9BQF6 1/20 0.62
▸ SENP6 Q9GZR1 1/20 0.62
▸ TDP1 Q9NUW8 5/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10305783 0.86 MEN1 (0.66) CSNK2A2CSNK2BCSNK2A1MAPTSMN1; SMN2
SCHEMBL5309179 0.83 TERT (0.73) TERTCSNK2A2CSNK2BCSNK2A1MAPT
SCHEMBL311865 0.83 TERT (0.68) TERTCSNK2A2CSNK2BCSNK2A1MAPT
SCHEMBL23299598 0.82 ESR1 (0.68) TERTCSNK2A2CSNK2BCSNK2A1MAPT
SCHEMBL13355967 0.81 CYP1A1 (0.70) CSNK2A2CSNK2BCSNK2A1MAPTCYP3A4
SCHEMBL312870 0.80 TERT (0.61) TERTCSNK2A2CSNK2BCSNK2A1MAPT
SCHEMBL4649959 0.79 TERT (1.00) TERTCSNK2A2CSNK2BCSNK2A1MAPT
SCHEMBL31322174 0.79 TERT (1.00) TERTCSNK2A2CSNK2BCSNK2A1MAPT
SCHEMBL24046928 0.77 CSNK2A2 (0.65) TERTCSNK2A2CSNK2BCSNK2A1MAPT
SCHEMBL15231415 0.77 CSNK2A2 (0.65) TERTCSNK2A2CSNK2BCSNK2A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230000121-A1 APIGENIN GLYCOSIDES FLAVOR ENHANCERS OHIO STATE INNOVATION FOUNDATION 2023-01-05 — — US disclosed
US-8293315-B2 Process for the preparation of active substance concentrate COGNIS IP MANAGEMENT GMBH (DE) 2012-10-23 — — US disclosed
US-8293315-B2 Process for the preparation of active substance concentrate COGNIS IP MANAGEMENT GMBH (DE) 2012-10-23 — — US disclosed
EP-1738738-B1 Microcapsules COGNIS IP MAN GMBH (DE) 2012-07-11 — — EP disclosed
EP-2060251-B1 Method for manufacturing active agent concentrates COGNIS IP MAN GMBH (DE) 2011-03-23 — — EP disclosed
US-20100009063-A1 Process for the preparation of active substance concentrate COGNIS IP MANAGEMENT GMBH (DE) 2010-01-14 — — US disclosed
US-20100009063-A1 Process for the preparation of active substance concentrate COGNIS IP MANAGEMENT GMBH (DE) 2010-01-14 — — US disclosed
EP-2060251-A1 Method for manufacturing active agent concentrates Cognis IP Management GmbH (DE) 2009-05-20 — — EP disclosed
EP-1623757-B1 Microcapsules (XXXII) COGNIS IP MAN GMBH (DE) 2009-02-11 — — EP disclosed
US-20080268024-A1 Compositions for Oral and/or Topical Administration COGNIS IP MANAGEMENT GMBH (DE) 2008-10-30 — — US disclosed
US-20080268024-A1 Compositions for Oral and/or Topical Administration COGNIS IP MANAGEMENT GMBH (DE) 2008-10-30 — — US disclosed
US-20080220101-A1 COMPOSITIONS OF EXTRACTS OF ALOE FOR ORAL ADMINISTRATION COGNIS IP MANAGEMENT GMBH (DE) 2008-09-11 — — US disclosed
US-20080220101-A1 COMPOSITIONS OF EXTRACTS OF ALOE FOR ORAL ADMINISTRATION COGNIS IP MANAGEMENT GMBH (DE) 2008-09-11 — — US disclosed
EP-1967197-A1 Use of preparations, purifications and extracts of aloe Cognis IP Management GmbH (DE) 2008-09-10 — — EP disclosed
WO-2008046521-A1 PREPARATION FOR ORAL ADMINISTRATION (II) COGNIS IP MANAGEMENT GMBH (DE) 2008-04-24 — — WO disclosed
WO-2008028585-A2 COSMETIC AND/OR PHARMACEUTICAL PREPARATIONS CONTAINING HOODIA EXTRACTS COGNIS IP MANAGEMENT GMBH (DE) 2008-03-13 — — WO disclosed
WO-2008028584-A1 PREPARATIONS FOR ORAL ADMINISTRATION (I) COGNIS IP MANAGEMENT GMBH (DE) 2008-03-13 — — WO disclosed
WO-2007068390-A1 PRE-MIXES FOR PERSONAL AND HOME CARE COMPOSITIONS COGNIS IP MANAGEMENT GMBH (DE) 2007-06-21 — — WO disclosed
EP-1798279-A1 Pre-mixes for personal and home care compositions Cognis IP Management GmbH (DE) 2007-06-20 — — EP disclosed
EP-1738738-A1 Microcapsules Cognis IP Management GmbH (DE) 2007-01-03 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080268024-A1 Compositions for Oral and/or Topical Administration FABP2, FABP6, CUTA TERT 2054/4885CSNK2A2 4555/4885CSNK2B 4617/4885
US-20080220101-A1 COMPOSITIONS OF EXTRACTS OF ALOE FOR ORAL ADMINISTRATION LIPE, ALOX15, ALOX5 TERT 4301/4885CSNK2A2 1678/4885CSNK2B 1760/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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