Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 15/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 14/20 | 1.00 |
| ▸ | HPGD | P15428 | 9/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 1.00 |
| ▸ | GAA | P10253 | 6/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 6/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 5/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 5/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.65 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4090734 | 0.98 | ALDH1A1 (0.97) | MAPTALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL1887318 | 0.98 | ALDH1A1 (0.97) | MAPTALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL1976488 | 0.97 | MAPT (0.94) | MAPTALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL14641131 | 0.86 | ALDH1A1 (0.80) | MAPTALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL10241785 | 0.86 | MAPT (0.75) | MAPTALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL8199434 | 0.85 | MAPT (0.85) | MAPTALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL2999543 | 0.84 | ADORA1 (0.82) | MAPTALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL8203239 | 0.84 | MAPT (0.72) | MAPTALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL3759273 | 0.84 | ALDH1A1 (0.73) | MAPTALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL3758303 | 0.84 | ALDH1A1 (0.72) | MAPTALDH1A1HPGDKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 472 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025042610-A1 | PIFITHRIN ANALOGUES AND METHODS OF TREATING RETT SYNDROME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-02-27 | — | — | WO | claimed |
| CN-111875615-A | Methoxybenzyl urea compound and application thereof | 济南大学 | 2020-11-03 | — | — | CN | claimed |
| US-20090298842-A1 | Novel therapeutic targets for the treatment of mycobacterial infections and compounds useful therefor | PATO JANOS | 2009-12-03 | — | — | US | claimed |
| US-20090018149-A1 | 4,5,6,7-tetrahydrobenzo[b]thiophene derivatives and methods for medical intervention against mycobacterial infections | AXXIMA PHARMACEUTICALS AG (DE) | 2009-01-15 | — | — | US | claimed |
| US-20050048887-A1 | Method and system for processing waste streams derived from the dehairing of animals | MONFORT, INC. | 2005-03-03 | — | — | US | claimed |
| EP-1492783-A1 | 4,5,6,7-TRETRAHYDROBENZO(B) THIOPHENE DERIVATIVES AND METHODS FOR MEDICAL INTERVENTION AGAINST MYCROBACTERIAL INFECTIONS | Axxima Pharmaceuticals AG (DE) | 2005-01-05 | — | — | EP | claimed |
| US-20040171603-A1 | Novel therapeutic targets for the treatment of mycobacterial infections and compounds useful therefor | VICHEM CHEMIE KFT (HU) | 2004-09-02 | — | — | US | claimed |
| US-20040063392-A1 | Method and system for processing waste streams derived from the dehairing of animals | MONFORT, INC. | 2004-04-01 | — | — | US | claimed |
| US-6712685-B2 | Method and system for processing waste products generated in an animal dehairing operation | MONFORT, INC. | 2004-03-30 | — | — | US | claimed |
| WO-2003084947-A1 | 4,5,6,7-TRETRAHYDROBENZO[B] THIOPHENE DERIVATIVES AND METHODS FOR MEDICAL INTERVENTION AGAINST MYCROBACTERIAL INFECTIONS | AXXIMA PHARMACEUTICALS AG (DE) | 2003-10-16 | — | — | WO | claimed |
| US-12624023-B2 | Sulfonylurea derivatives and uses thereof | NodThera Limited (GB) | 2026-05-12 | — | — | US | disclosed |
| US-20260116872-A1 | THIOPHENE BASED APYRASE INHIBITORS | TEXAS CROP SCIENCE INC (US) | 2026-04-30 | — | — | US | disclosed |
| WO-2026090564-A2 | THIOPHENE BASED APYRASE INHIBITORS | TEXAS CROP SCIENCE, INC. (US) | 2026-04-30 | — | — | WO | disclosed |
| EP-3983407-B1 | SULFONYLUREA DERIVATIVES AND USES THEREOF | NODTHERA LTD (GB) | 2025-11-12 | — | — | EP | disclosed |
| EP-4568971-A1 | ANTAGONISTS OF 5-HYDROXYTRYPTAMINE RECEPTOR SUBTYPE 2B | Vanderbilt University (US) | 2025-06-18 | — | — | EP | disclosed |
| US-4172831-A | CENTRAL NERVOUS SYSTEM | LILLY INDUSTRIES LIMITED (GB) | 1979-10-30 | — | — | US | disclosed |
| US-4115574-A | CNS ACTIVITY | LILLY INDUSTRIES LIMITED (GB) | 1978-09-19 | — | — | US | disclosed |
| US-4115568-A | CNS ACTIVITY | LILLY INDUSTRIES LIMITED (GB) | 1978-09-19 | — | — | US | disclosed |
| US-4013681-A | SUGAR CANE RIPENERS | HAWAIIAN SUGAR PLANTERS' ASSOCIATION (US) | 1977-03-22 | — | — | US | disclosed |
| US-3989505-A | Use of polycyclic thiophene compounds as ripeners for sugarcane | HAWAIIAN SUGAR PLANTERS' ASSOCIATION (US) | 1976-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298842-A1 | Novel therapeutic targets for the treatment of mycobacterial infections and compounds useful therefor | PKLR, MASTL, BPGM | MAPT 3062/4885ALDH1A1 4718/4885HPGD 964/4885 |
| US-20260116872-A1 | THIOPHENE BASED APYRASE INHIBITORS | SRR, APEH, OSR1 | MAPT 4472/4885ALDH1A1 2701/4885HPGD 3033/4885 |
| US-12624023-B2 | Sulfonylurea derivatives and uses thereof | PYCARD, NOD1, NLRP3 | MAPT 4223/4885ALDH1A1 561/4885HPGD 969/4885 |
| US-20040171603-A1 | Novel therapeutic targets for the treatment of mycobacterial infections and compounds useful therefor | PKLR, PKN1, PKMYT1 | MAPT 2046/4885ALDH1A1 4655/4885HPGD 852/4885 |
| US-20090018149-A1 | 4,5,6,7-tetrahydrobenzo[b]thiophene derivatives and methods for medical intervention against mycobacterial infections | STK4, SBK3, STK17B | MAPT 2119/4885ALDH1A1 4146/4885HPGD 2459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.