SCHEMBL5294134

SCHEMBL5294134

CN(c1ccccc1)c1ccc(C(C)(C)C)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
RAB9A P51151 3/20 0.50
NPSR1 Q6W5P4 2/20 0.50
NR3C2 P08235 1/20 0.44
CYP2D6 P10635 1/20 0.43
TSHR P16473 2/20 0.42
LMNA P02545 3/20 0.41
TYR P14679 1/20 0.41
ALDH1A1 P00352 2/20 0.41
S1PR4 O95977 1/20 0.41
HSP90AA1 P07900 1/20 0.41
HPGD P15428 1/20 0.41
S1PR1 P21453 1/20 0.41
MAPK1 P28482 1/20 0.41
CCR6 P51684 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TLR9 Q9NR96 1/20 0.41
CHKA P35790 2/20 0.40
KCNN4 O15554 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14466522 0.94 MEN1 (0.46) MEN1KMT2ARAB9ANPSR1NR3C2
SCHEMBL14466288 0.94 MEN1 (0.46) MEN1KMT2ARAB9ANPSR1NR3C2
SCHEMBL1134090 0.91 TSHR (0.50) MEN1KMT2ARAB9ANPSR1TSHR
SCHEMBL13367484 0.90 KIF11 (0.47) MEN1KMT2ARAB9ANPSR1TSHR
SCHEMBL18627688 0.90 KIF11 (0.47) MEN1KMT2ARAB9ANPSR1TSHR
SCHEMBL23381503 0.86 CHKA (0.43) MEN1KMT2ARAB9ANPSR1CYP2D6
SCHEMBL14489808 0.86 MEN1 (0.41) MEN1KMT2ARAB9ANPSR1NR3C2
SCHEMBL13720556 0.84 L3MBTL1 (0.50) MEN1KMT2ARAB9ANPSR1CYP2D6
SCHEMBL6935203 0.84 L3MBTL1 (0.50) MEN1KMT2ARAB9ANPSR1CYP2D6
SCHEMBL14163852 0.84 L3MBTL1 (0.50) MEN1KMT2ARAB9ANPSR1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4137551-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-02-22 EP disclosed
US-11584753-B2 Bisbenzofuran-fused 2,8-diaminoindeno[1,2-b]fluorene derivatives and related compounds as materials for organic electroluminescent devices (OLED) MERCK PATENT GMBH (DE) 2023-02-21 US disclosed
US-20220393117-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-12-08 US disclosed
US-20210205800-A1 YLIDE-FUNCTIONALISED PHOSPHANES FOR USE IN METAL COMPLEXES AND HOMOGENEOUS CATALYSIS UMICORE AG & CO. KG (DE) 2021-07-08 US disclosed
US-10940470-B2 Ylide-functionalised phosphanes for use in metal complexes and homogeneous catalysis UMICORE AG & CO. KG (DE) 2021-03-09 US disclosed
EP-3544984-B1 BISBENZOFURAN-FUSED 2,8-DIAMINOINDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) MERCK PATENT GMBH (DE) 2020-12-23 EP disclosed
WO-2020159279-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME 주식회사 엘지화학 2020-08-06 WO disclosed
US-20200164354-A1 YLIDE-FUNCTIONALISED PHOSPHANES FOR USE IN METAL COMPLEXES AND HOMOGENEOUS CATALYSIS UMICORE AG & CO. KG (DE) 2020-05-28 US disclosed
US-20190315764-A1 BISBENZOFURAN-FUSED 2,8-DIAMINOINDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) MERCK PATENT GMBH (DE) 2019-10-17 US disclosed
EP-3522191-A1 PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, METAL COMPLEX DYE, DYE SOLUTION, AND OXIDE SEMICONDUCTOR ELECTRODE FUJIFILM Corporation (JP) 2019-08-07 EP disclosed
US-20100108997-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-05-06 US disclosed
US-7674828-B2 Urea antagonists of P2Y1receptor useful in the treatment of thrombotic conditions BRISTOL-MYERS SQUIBB COMPANY (US) 2010-03-09 US disclosed
US-20090326243-A1 Ligands for transition-metals and methods of use THE HONG KONG POLYTECHNIC UNIVERSITY (HK) 2009-12-31 US disclosed
WO-2009151957-A1 INITIATOR SYSTEM CONTAINING A DIARYLAKYLAMINE DERIVATIVE, HARDENABLE COMPOSITION AND USE THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-12-17 WO disclosed
EP-2133064-A1 Initiator system containing a diarylalkylamine derivate, hardenable composition and use thereof 3M Innovative Properties Company (US) 2009-12-16 EP disclosed
US-20090291945-A1 CYSTEINE PROTEASE INHIBITORS TEIJIN PHARMA LIMITED (JP) 2009-11-26 US disclosed
US-20080280905-A1 UREA ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS BRISTOL MYERS SQUIBB COMPANY (US) 2008-11-13 US disclosed
EP-1313560-B1 CATALYST FOR AROMATIC C-O, C-N, and C-C BOND FORMATION UNIV YALE (US) 2007-12-19 EP disclosed
US-6562989-B2 Bicyclopentyl iron ligand and transition metal catalyst YALE UNIVERSITY 2003-05-13 US disclosed
US-20030008768-A1 Catalyst for aromatic C-O, C-N, and C-C bond formation NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-01-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220393117-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NPY1R, NPY2R, KISS1R MEN1 1077/4885KMT2A 1124/4885RAB9A 448/4885
US-20080280905-A1 UREA ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS P2RY1, P2RY11, P2RY2 MEN1 3173/4885KMT2A 4568/4885RAB9A 3263/4885
US-20090291945-A1 CYSTEINE PROTEASE INHIBITORS CTSE, SPINT2, CTSF MEN1 1994/4885KMT2A 3986/4885RAB9A 658/4885
US-20090326243-A1 Ligands for transition-metals and methods of use PDK4, PDXK, PDK3 MEN1 1961/4885KMT2A 1611/4885RAB9A 4038/4885
US-20190315764-A1 BISBENZOFURAN-FUSED 2,8-DIAMINOINDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) OCIAD1, OCIAD2, AOC1 MEN1 2637/4885KMT2A 2997/4885RAB9A 1290/4885
US-20100108997-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OR10J3, OCIAD1, OCIAD2 MEN1 3828/4885KMT2A 3622/4885RAB9A 1308/4885
US-11584753-B2 Bisbenzofuran-fused 2,8-diaminoindeno[1,2-b]fluorene derivatives and related compounds as materials for organic electroluminescent devices (OLED) OCIAD1, OCIAD2, AOC1 MEN1 2637/4885KMT2A 2997/4885RAB9A 1290/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.