SCHEMBL13385366

SCHEMBL13385366

Cc1cc(F)c(F)c(F)c1C(C)C

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 1/20 0.33
BCL2L1 Q07817 1/20 0.33
MCL1 Q07820 1/20 0.33
BCL2L2 Q92843 1/20 0.33
RAPGEF4 Q8WZA2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15085220 0.84 BCL2 (0.32) BCL2BCL2L1MCL1BCL2L2RAPGEF4
SCHEMBL20288575 0.83 BCL2 (0.31) BCL2BCL2L1MCL1BCL2L2
SCHEMBL20223463 0.81 BCL2 (0.33) BCL2BCL2L1MCL1BCL2L2
SCHEMBL12370995 0.81 BCL2 (0.33) BCL2BCL2L1MCL1BCL2L2RAPGEF4
SCHEMBL9945872 0.80 CA1 (0.31)
SCHEMBL24633208 0.79 BCL2 (0.32) BCL2BCL2L1MCL1BCL2L2RAPGEF4
SCHEMBL18882778 0.78 BCL2 (0.34) BCL2BCL2L1MCL1BCL2L2
SCHEMBL24981463 0.77 BCL2 (0.33) BCL2BCL2L1MCL1BCL2L2
SCHEMBL13377140 0.76 GABRA1 (0.31)
SCHEMBL15200466 0.76 BCL2 (0.33) BCL2BCL2L1MCL1BCL2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100102710-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-04-29 US disclosed
US-20090261714-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-10-22 US disclosed
US-20090184631-A1 Novel red electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-07-23 US disclosed
US-20090184629-A1 Novel red electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-07-23 US disclosed
US-20090153037-A1 Novel red electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-06-18 US disclosed
US-20090145483-A1 Novel electroluminescent compounds and organic electroluminescent device suing the same GRACEL DISPLAY INC. (KR) 2009-06-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090145483-A1 Novel electroluminescent compounds and organic electroluminescent device suing the same LEF1, ODC1, AOC2 BCL2 4117/4885BCL2L1 996/4885MCL1 1269/4885
US-20090261714-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same AOX1, ODC1, LEF1 BCL2 3892/4885BCL2L1 742/4885MCL1 1116/4885
US-20090184631-A1 Novel red electroluminescent compounds and organic electroluminescent device using the same ALDH1A2, ODC1, NDUFS2 BCL2 4403/4885BCL2L1 1370/4885MCL1 1253/4885
US-20090153037-A1 Novel red electroluminescent compounds and organic electroluminescent device using the same NDUFS2, ALDH1A2, ODC1 BCL2 4401/4885BCL2L1 1419/4885MCL1 1338/4885
US-20090184629-A1 Novel red electroluminescent compounds and organic electroluminescent device using the same IK, TYR, EYA2 BCL2 4521/4885BCL2L1 2991/4885MCL1 2974/4885
US-20100102710-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same ODC1, AOX1, OR10J3 BCL2 4135/4885BCL2L1 973/4885MCL1 1599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.