Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPS1 | P31327 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.34 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | HTR1F | P30939 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 2/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17680658 | 0.86 | HTR1F (0.41) | CPS1L3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL6141006 | 0.81 | L3MBTL1 (0.61) | CPS1L3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL2304821 | 0.80 | ALDH1A1 (0.51) | CPS1L3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL23175682 | 0.79 | KMT2A (0.55) | CPS1L3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL30833732 | 0.79 | DGAT1 (0.58) | CPS1L3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL13427 | 0.79 | DGAT1 (0.58) | CPS1L3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL9156406 | 0.76 | GAA (0.49) | CPS1L3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL28026637 | 0.76 | L3MBTL1 (0.55) | CPS1L3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL28026635 | 0.76 | L3MBTL1 (0.55) | CPS1L3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL256756 | 0.75 | CES2 (0.43) | ALDH1A1MAPTCES2CES1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011044187-A1 | IMINOTHIADIAZINE DIOXIDE COMPOUNDS AS BACE INHIBITORS, COMPOSITIONS, AND THEIR USE | SCHERING CORPORATION (US) | 2011-04-14 | — | — | WO | disclosed |