Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.49 |
| ▸ | ITGB7 | P26010 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMO | Q99835 | 2/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2364824 | 0.73 | CES2 (0.51) | ALDH1A1MAPTPOLBHPGDITGA4 | |
| SCHEMBL17717930 | 0.71 | ALDH1A1 (0.53) | ALDH1A1MAPTPOLBITGA4ITGB7 | |
| SCHEMBL9980773 | 0.68 | ALDH1A1 (0.57) | ALDH1A1MAPTLMNASMN1; SMN2HSD17B10 | |
| SCHEMBL17358740 | 0.68 | MAPT (0.49) | ALDH1A1MAPTPOLBHPGDITGA4 | |
| SCHEMBL12218050 | 0.68 | MEN1 (0.82) | ALDH1A1MAPTPOLBHPGDITGA4 | |
| SCHEMBL2672856 | 0.68 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNASMN1; SMN2HSD17B10 | |
| SCHEMBL3132028 | 0.68 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNASMN1; SMN2HSD17B10 | |
| SCHEMBL17717951 | 0.67 | ALDH1A1 (0.60) | ALDH1A1MAPTLMNASMN1; SMN2HSD17B10 | |
| SCHEMBL17717928 | 0.67 | ALDH1A1 (0.50) | ALDH1A1MAPTHPGDITGA4ITGB7 | |
| SCHEMBL472396 | 0.67 | ALDH1A1 (0.56) | ALDH1A1MAPTLMNASMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100093611-A1 | COMPOUNDS AND METHODS FOR TREATING OR PREVENTING AUTOIMMUNE DISEASES | AVALON PHARMACEUTICALS, INC. | 2010-04-15 | — | — | US | disclosed |
| US-20100093611-A1 | COMPOUNDS AND METHODS FOR TREATING OR PREVENTING AUTOIMMUNE DISEASES | AVALON PHARMACEUTICALS, INC. | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093611-A1 | COMPOUNDS AND METHODS FOR TREATING OR PREVENTING AUTOIMMUNE DISEASES | IKBKB, IKBKG, NFKBIA | ALDH1A1 3651/4885MAPT 3345/4885POLB 335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.