SCHEMBL13408754

SCHEMBL13408754

c1ccc(N(c2cccc3ccccc23)c2cc3cc(N(c4ccccc4)c4cccc5ccccc45)c4ccccc4c3c3ccccc23)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 12/20 0.42
CYP1A2 P05177 3/20 0.35
ALDH1A1 P00352 3/20 0.35
HSD17B10 Q99714 3/20 0.35
HPGD P15428 2/20 0.35
THRB P10828 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
HIF1A Q16665 2/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
ERBB2 P04626 1/20 0.33
FYN P06241 1/20 0.33
MAOA P21397 1/20 0.33
ACHE P22303 1/20 0.33
AHR P35869 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
CASP1 P29466 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13408923 0.91 SIGMAR1 (0.37) SIGMAR1ALDH1A1HSD17B10HPGDL3MBTL1
SCHEMBL13408902 0.91 ALDH1A1 (0.38) SIGMAR1ALDH1A1HSD17B10HPGDL3MBTL1
SCHEMBL14066878 0.89 SIGMAR1 (0.41) SIGMAR1CYP1A2ALDH1A1HSD17B10HPGD
SCHEMBL22669853 0.88 SIGMAR1 (0.43) SIGMAR1CYP1A2ALDH1A1HSD17B10HPGD
SCHEMBL13320935 0.88 SIGMAR1 (0.46) SIGMAR1CYP1A2ALDH1A1HSD17B10HPGD
SCHEMBL76828 0.88 SIGMAR1 (0.50) SIGMAR1CYP1A2ALDH1A1HSD17B10HPGD
SCHEMBL29527814 0.88 SIGMAR1 (0.50) SIGMAR1CYP1A2ALDH1A1HSD17B10HPGD
SCHEMBL13408933 0.87 GPR84 (0.39) SIGMAR1CYP1A2ALDH1A1HSD17B10HPGD
SCHEMBL2701507 0.86 SIGMAR1 (0.47) SIGMAR1CYP1A2ALDH1A1HSD17B10HPGD
SCHEMBL1249647 0.86 SIGMAR1 (0.47) SIGMAR1CYP1A2ALDH1A1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11233201-B2 Organic electroluminescent devices and preparation methods thereof KUNSHAN GO-VISIONOX OPTO-ELECTRONICS CO., LTD. (CN) 2022-01-25 US disclosed
US-10693107-B2 Organic electroluminescence device having RGB pixel areas BEIJING VISIONOX TECHNOLOGY CO., LTD. (CN) 2020-06-23 US disclosed
US-20170373276-A1 ORGANIC ELECTROLUMINESCENCE DEVICE HAVING RGB PIXEL AREAS BEIJING VISIONOX TECHNOLOGY CO., LTD. (CN) 2017-12-28 US disclosed
EP-3242343-A1 ORGANIC ELECTROLUMINESCENCE DEVICE HAVING RGB PIXEL AREAS Beijing Visionox Technology Co., Ltd. (CN) 2017-11-08 EP disclosed
US-20100096982-A1 Novel organic electroluminescent compounds and organic electrouminescent device using the same GRACEL DISPLAY INC. (KR) 2010-04-22 US disclosed
US-20100096982-A1 Novel organic electroluminescent compounds and organic electrouminescent device using the same GRACEL DISPLAY INC. (KR) 2010-04-22 US disclosed
US-20100019663-A1 FUSED AROMATIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING ORGANIC LAYER COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2010-01-28 US disclosed
US-20100019663-A1 FUSED AROMATIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING ORGANIC LAYER COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2010-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100096982-A1 Novel organic electroluminescent compounds and organic electrouminescent device using the same OCIAD1, OR10J3, ORMDL3 SIGMAR1 731/4885CYP1A2 1013/4885ALDH1A1 208/4885
US-10693107-B2 Organic electroluminescence device having RGB pixel areas RHEB, CYBA, RUVBL2 SIGMAR1 2521/4885CYP1A2 2306/4885ALDH1A1 2699/4885
US-20100019663-A1 FUSED AROMATIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING ORGANIC LAYER COMPRISING THE SAME OCIAD1, OCIAD2, APOL1 SIGMAR1 1417/4885CYP1A2 137/4885ALDH1A1 414/4885
US-20170373276-A1 ORGANIC ELECTROLUMINESCENCE DEVICE HAVING RGB PIXEL AREAS RUVBL2, RHEB, RUVBL1 SIGMAR1 2666/4885CYP1A2 2668/4885ALDH1A1 3055/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.