Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1410180 | 1.00 | LMNA (0.40) | LMNAKDM4EALDH1A1HPGDPOLB | |
| SCHEMBL22263664 | 1.00 | LMNA (0.40) | LMNAKDM4EALDH1A1HPGDPOLB | |
| SCHEMBL3434470 | 0.99 | LMNA (0.41) | LMNAKDM4EALDH1A1HPGDPOLB | |
| SCHEMBL7269169 | 0.93 | LMNA (0.37) | LMNAKDM4EALDH1A1HPGDPOLB | |
| Maleic Anhydride SCHEMBL7262306 | 0.89 | ALDH1A1 (0.34) | LMNAKDM4EALDH1A1HPGDPOLB | |
| Maleic Anhydride SCHEMBL7262875 | 0.88 | ALDH1A1 (0.35) | LMNAKDM4EALDH1A1HPGDPOLB | |
| SCHEMBL22263835 | 0.87 | ALDH1A1 (0.44) | LMNAKDM4EALDH1A1HPGDPOLB | |
| SCHEMBL6276583 | 0.87 | ALDH1A1 (0.34) | LMNAKDM4EALDH1A1HPGDPOLB | |
| SCHEMBL22344717 | 0.86 | LMNA (0.38) | LMNAKDM4EALDH1A1HPGDPOLB | |
| SCHEMBL11909235 | 0.86 | ALDH1A1 (0.45) | LMNAKDM4EALDH1A1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099906-A1 | GENERATION OF ENDO- AND/OR EXO-NORBORNENECARBOXALDEHYDE AS AN INTERMEDIATE TO FUNCTIONALIZED NORBORNENES | PROMERUS LLC (US) | 2010-04-22 | — | — | US | disclosed |
| US-20100099906-A1 | GENERATION OF ENDO- AND/OR EXO-NORBORNENECARBOXALDEHYDE AS AN INTERMEDIATE TO FUNCTIONALIZED NORBORNENES | PROMERUS LLC (US) | 2010-04-22 | — | — | US | disclosed |
| WO-2009061723-A1 | GENERATION OF ENDO- AND/OR EXO-NORBORNENECARBOXALDEHYDE AS AN INTERMEDIATE TO FUNCTIONALIZED NORBORNENES | PROMERUS, LLC (US) | 2009-05-14 | — | — | WO | disclosed |
| US-20090118539-A1 | forming diastereomeric mixture of norbornenecarbonitrile via Diels-Alder reaction, separating, converting to diastereomeric norbornenecarboxaldehyde, and norbornenecarboxylic acid and alcohol; methathesis ring-opening polymerization | PROMERUS, LLC (US) | 2009-05-07 | — | — | US | disclosed |
| US-20090118539-A1 | forming diastereomeric mixture of norbornenecarbonitrile via Diels-Alder reaction, separating, converting to diastereomeric norbornenecarboxaldehyde, and norbornenecarboxylic acid and alcohol; methathesis ring-opening polymerization | PROMERUS, LLC (US) | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118539-A1 | forming diastereomeric mixture of norbornenecarbonitrile via Diels-Alder reaction, separating, converting to diastereomeric norbornenecarboxaldehyde, and norbornenecarboxylic acid and alcohol; methathesis ring-opening polymerization | MMAB, ADH1C, OXER1 | LMNA 1610/4885KDM4E 3566/4885ALDH1A1 50/4885 |
| US-20100099906-A1 | GENERATION OF ENDO- AND/OR EXO-NORBORNENECARBOXALDEHYDE AS AN INTERMEDIATE TO FUNCTIONALIZED NORBORNENES | GNE, GALE, EXOSC5 | LMNA 1713/4885KDM4E 2962/4885ALDH1A1 230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.