Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | EPOR | P19235 | 2/20 | 0.36 |
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13416276 | 0.94 | ITGB3 (0.41) | ITGB3ITGA2BLTA4HEPORLNPEP | |
| SCHEMBL13416281 | 0.86 | ACHE (0.44) | LTA4HEPORLNPEPERAP2DPP8 | |
| SCHEMBL13417056 | 0.84 | FFAR1 (0.41) | LTA4HGSRF2PTGS2 | |
| SCHEMBL13416252 | 0.83 | PTGS2 (0.39) | ITGB3ITGA2BLTA4HPTGS2 | |
| SCHEMBL16124585 | 0.82 | THRB (0.48) | ITGB3ITGA2BLTA4HEPORLNPEP | |
| SCHEMBL13416870 | 0.82 | NPY4R (0.38) | ITGB3ITGA2B | |
| SCHEMBL13416420 | 0.81 | FFAR1 (0.37) | LTA4HF2PTGS2 | |
| SCHEMBL16124583 | 0.81 | THRB (0.47) | ITGB3ITGA2BLTA4HLNPEPERAP2 | |
| SCHEMBL13396440 | 0.81 | ITGB3 (0.40) | ITGB3ITGA2BLTA4HLNPEPERAP2 | |
| SCHEMBL14135115 | 0.81 | ACHE (0.44) | LTA4HEPORLNPEPDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099729-A1 | NITRIC OXIDE DONOR COMPOUNDS | NICOX S.A. (FR) | 2010-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099729-A1 | NITRIC OXIDE DONOR COMPOUNDS | NOS3, NOS2, NOS1 | ITGB3 211/4885ITGA2B 313/4885LTA4H 1146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.