Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.39 |
| ▸ | LTA4H | P09960 | 4/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | MC5R | P33032 | 1/20 | 0.36 |
| ▸ | MC1R | Q01726 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13416630 | 0.93 | LTA4H (0.39) | ACHEFFAR1LTA4HMC4RMC5R | |
| SCHEMBL13416416 | 0.88 | ACHE (0.41) | ACHEFFAR1LTA4H | |
| SCHEMBL13416257 | 0.86 | ACHE (0.43) | ACHE | |
| SCHEMBL13417056 | 0.86 | FFAR1 (0.41) | FFAR1LTA4HFFAR4 | |
| SCHEMBL13416281 | 0.85 | ACHE (0.44) | ACHELTA4H | |
| SCHEMBL13396478 | 0.82 | PTGS1 (0.40) | ACHEFFAR1LTA4HFFAR4 | |
| SCHEMBL13416411 | 0.82 | ACHE (0.40) | ACHE | |
| SCHEMBL13416874 | 0.80 | MTNR1A (0.37) | ACHE | |
| SCHEMBL14135115 | 0.80 | ACHE (0.44) | ACHELTA4H | |
| SCHEMBL13417046 | 0.79 | NAALAD2 (0.44) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099729-A1 | NITRIC OXIDE DONOR COMPOUNDS | NICOX S.A. (FR) | 2010-04-22 | — | — | US | disclosed |
| WO-2008095841-A2 | NITRIC OXIDE DONOR COMPOUNDS | NICOX S.A. (FR) | 2008-08-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099729-A1 | NITRIC OXIDE DONOR COMPOUNDS | NOS3, NOS2, NOS1 | ACHE 540/4885FFAR1 1241/4885LTA4H 1146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.