Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 12/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13416241 | 0.93 | ACHE (0.41) | ACHE | |
| SCHEMBL13416416 | 0.88 | ACHE (0.41) | ACHESLC7A5KMT2A | |
| SCHEMBL13417055 | 0.86 | ACHE (0.40) | ACHE | |
| SCHEMBL13416281 | 0.85 | ACHE (0.44) | ACHE | |
| SCHEMBL13416252 | 0.84 | PTGS2 (0.39) | ALOX5 | |
| SCHEMBL13416274 | 0.83 | ACHE (0.44) | ACHE | |
| SCHEMBL13416453 | 0.82 | ACHE (0.41) | ACHE | |
| SCHEMBL16124570 | 0.82 | ALOX5 (0.52) | ACHEALOX5 | |
| SCHEMBL13416411 | 0.81 | ACHE (0.40) | ACHEKMT2A | |
| SCHEMBL13396357 | 0.81 | ALOX5 (0.44) | ACHEALOX5SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099729-A1 | NITRIC OXIDE DONOR COMPOUNDS | NICOX S.A. (FR) | 2010-04-22 | — | — | US | disclosed |
| WO-2008095841-A2 | NITRIC OXIDE DONOR COMPOUNDS | NICOX S.A. (FR) | 2008-08-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099729-A1 | NITRIC OXIDE DONOR COMPOUNDS | NOS3, NOS2, NOS1 | ACHE 540/4885ALOX5 72/4885SLC7A5 4181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.