SCHEMBL134273

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21845489	0.92	KMO (0.50)	KMOHDAC8ATMTDP1L3MBTL1
	SCHEMBL12551618	0.89	KMO (0.50)	KMOHDAC8ATMTDP1L3MBTL1
	SCHEMBL21397936	0.87	KMO (0.45)	KMOHDAC8ATMTDP1L3MBTL1
	SCHEMBL18643521	0.84	KMO (0.43)	KMOHDAC8ATMTDP1L3MBTL1
	SCHEMBL16858233	0.84	KMO (0.72)	KMOHDAC8ATMTDP1L3MBTL1
	SCHEMBL134265	0.82	CDC25B (0.55)	ATML3MBTL1ERCC5FEN1
	SCHEMBL11183749	0.82	ATM (0.74)	KMOHDAC8ATMTDP1L3MBTL1
	SCHEMBL134274	0.82	ALDH1A1 (0.62)	ATMTDP1L3MBTL1PBRM1
	SCHEMBL12551824	0.81	KMO (0.53)	KMOHDAC8ATMTDP1L3MBTL1
	SCHEMBL133749	0.81	KMO (0.53)	KMOHDAC8ATMTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.