SCHEMBL134265

SCHEMBL134265

O=C(c1ccc(-c2ccccc2)cc1)c1nc(C(=O)c2ccc(-c3ccccc3)cc2)nc(C(=O)c2nc(C(=O)c3ccc(-c4ccccc4)cc3)nc(C(=O)c3ccc(-c4ccccc4)cc3)n2)n1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 1/20 0.55
ATM Q13315 1/20 0.55
RAB9A P51151 4/20 0.53
MAPT P10636 3/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
LMNA P02545 2/20 0.53
SMN1; SMN2 Q16637 5/20 0.52
POLB P06746 1/20 0.50
MAPK1 P28482 1/20 0.50
NPC1 O15118 2/20 0.48
CTDSP1 Q9GZU7 1/20 0.48
L3MBTL1 Q9Y468 2/20 0.47
PTPN1 P18031 1/20 0.47
GSK3B P49841 1/20 0.47
ALDH1A1 P00352 1/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA9 Q16790 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21974835 0.90 CDC25B (0.50) CDC25BATMRAB9AMAPTMEN1
SCHEMBL12551616 0.87 CDC25B (0.51) CDC25BATMRAB9AMAPTMEN1
SCHEMBL13351686 0.87 CDC25B (0.47) CDC25BATMRAB9AMAPTMEN1
SCHEMBL134274 0.87 ALDH1A1 (0.62) ATMRAB9AMAPTMEN1KMT2A
SCHEMBL28489651 0.84 ALDH1A1 (0.65) ATMRAB9AMAPTMEN1KMT2A
SCHEMBL132971 0.83 L3MBTL1 (0.48) CDC25BATMRAB9AMAPTMEN1
SCHEMBL134273 0.82 KMO (0.58) ATML3MBTL1ERCC5FEN1
SCHEMBL232724 0.82 RAB9A (0.74) CDC25BATMRAB9AMAPTMEN1
SCHEMBL20696596 0.82 CDC25B (0.46) CDC25BATMRAB9AMAPTMEN1
SCHEMBL15159197 0.82 CDC25B (0.40) CDC25BATMRAB9AMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11535640-B2 Metal complexes MERCK PATENT GMBH (DE) 2022-12-27 US disclosed
US-11145828-B2 Metal complexes MERCK PATENT GMBH (DE) 2021-10-12 US disclosed
US-11136343-B2 Binuclear metal complexes for use as emitters in organic electroluminescent devices MERCK PATENT GMBH (DE) 2021-10-05 US disclosed
US-10889604-B2 Binuclear and trinuclear metal complexes composed of two inter-linked tripodal hexadentate ligands for use in electroluminescent devices MERCK PATENT GMBH 2021-01-12 US disclosed
US-20200207794-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2020-07-02 US disclosed
US-10636990-B2 Organic electroluminescence device MERCK PATENT GMBH (DE) 2020-04-28 US disclosed
EP-2748878-B1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2020-04-01 EP disclosed
US-20190292210-A1 BINUCLEAR METAL COMPLEXES FOR USE AS EMITTERS IN ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2019-09-26 US disclosed
US-20190252628-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2019-08-15 US disclosed
US-20190202851-A1 BINUCLEAR AND TRINUCLEAR METAL COMPLEXES COMPOSED OF TWO INTER-LINKED TRIPODAL HEXADENTATE LIGANDS FOR USE IN ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2019-07-04 US disclosed
US-20120056169-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH PATENTS & SCIENTIFIC INFORMATION (DE) 2012-03-08 US disclosed
US-20120037896-A1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2012-02-16 US disclosed
US-20120037896-A1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2012-02-16 US disclosed
US-20110284831-A1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2011-11-24 US disclosed
US-20110284831-A1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2011-11-24 US disclosed
US-20110140043-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2011-06-16 US disclosed
US-20110140043-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2011-06-16 US disclosed
US-20110108818-A1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2011-05-12 US disclosed
US-20110108818-A1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2011-05-12 US disclosed
WO-2010115498-A1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2010-10-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190202851-A1 BINUCLEAR AND TRINUCLEAR METAL COMPLEXES COMPOSED OF TWO INTER-LINKED TRIPODAL HEXADENTATE LIGANDS FOR USE IN ELECTROLUMINESCENT DEVICES PARN, PUF60, PARG CDC25B 4583/4885ATM 3697/4885RAB9A 3136/4885
US-11145828-B2 Metal complexes AP1M1, AP2M1, AP3M1 CDC25B 4037/4885ATM 4131/4885RAB9A 2280/4885
US-20190252628-A1 METAL COMPLEXES AP1M1, AP2M1, AP3M1 CDC25B 4037/4885ATM 4131/4885RAB9A 2280/4885
US-20190292210-A1 BINUCLEAR METAL COMPLEXES FOR USE AS EMITTERS IN ORGANIC ELECTROLUMINESCENT DEVICES AP2M1, MCU, AP3M1 CDC25B 3858/4885ATM 4246/4885RAB9A 1967/4885
US-20110140043-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICE L1CAM, SLCO4C1, GJA1 CDC25B 3293/4885ATM 3275/4885RAB9A 2620/4885
US-10889604-B2 Binuclear and trinuclear metal complexes composed of two inter-linked tripodal hexadentate ligands for use in electroluminescent devices PARN, PUF60, PARG CDC25B 4583/4885ATM 3697/4885RAB9A 3136/4885
US-20200207794-A1 METAL COMPLEXES IMMT, MCU, SOD1 CDC25B 4259/4885ATM 4048/4885RAB9A 2000/4885
US-11535640-B2 Metal complexes IMMT, MCU, SOD1 CDC25B 4259/4885ATM 4048/4885RAB9A 2000/4885
US-11136343-B2 Binuclear metal complexes for use as emitters in organic electroluminescent devices AP2M1, MCU, AP3M1 CDC25B 3858/4885ATM 4246/4885RAB9A 1967/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.