Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 9/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 8/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8469537 | 0.89 | ALDH1A1 (0.39) | KEAP1ALDH1A1LMNANFE2L2HPGD | |
| SCHEMBL8469817 | 0.87 | KEAP1 (0.40) | KEAP1ALDH1A1LMNAL3MBTL1NFE2L2 | |
| Trifluoromethanesulfonic Acid SCHEMBL4426555 | 0.84 | ALDH1A1 (0.37) | KEAP1ALDH1A1LMNAHPGDKMT2A | |
| SCHEMBL8469668 | 0.84 | ALDH1A1 (0.37) | KEAP1ALDH1A1LMNANFE2L2HPGD | |
| SCHEMBL8472099 | 0.83 | TP53 (0.35) | KEAP1ALDH1A1LMNANFE2L2MAPT | |
| SCHEMBL8469304 | 0.81 | TSHR (0.39) | KEAP1ALDH1A1LMNAL3MBTL1NFE2L2 | |
| SCHEMBL8470372 | 0.80 | TP53 (0.37) | KEAP1ALDH1A1LMNANFE2L2MAPT | |
| SCHEMBL8066342 | 0.79 | ALDH1A1 (0.38) | KEAP1ALDH1A1LMNANFE2L2HPGD | |
| SCHEMBL374354 | 0.79 | KMT2A (0.33) | ALDH1A1LMNAHPGDKMT2AMAPT | |
| SCHEMBL8469774 | 0.76 | LMNA (0.39) | KEAP1LMNANFE2L2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6002007-A | Special chemiluminescent acridine derivatives and the use thereof in luminescence immunoassays | DADE BEHRING MARBURG GMBH (DE) | 1999-12-14 | — | — | US | claimed |
| US-6002007-A | Special chemiluminescent acridine derivatives and the use thereof in luminescence immunoassays | DADE BEHRING MARBURG GMBH (DE) | 1999-12-14 | — | — | US | disclosed |
| US-5879953-A | Special chemiluminescent acridine derivatives and the use thereof in luminescence immunoassays | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-09 | — | — | US | disclosed |
| US-5783696-A | Special chemiluminescent acridine derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-21 | — | — | US | disclosed |