Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 8/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3477976 | 0.78 | FAAH (0.54) | HDAC6FAAHELANEPIK3CA | |
| SCHEMBL13436727 | 0.74 | FAAH (0.54) | HDAC6FAAHELANEPIK3CASYK | |
| SCHEMBL3477848 | 0.72 | FAAH (0.58) | HDAC6FAAHELANEPIK3CA | |
| SCHEMBL13436723 | 0.72 | FAAH (0.58) | HDAC6FAAHELANEPIK3CA | |
| SCHEMBL16380661 | 0.69 | FAAH (0.63) | HDAC6FAAHELANEPIK3CA | |
| SCHEMBL13436761 | 0.69 | HDAC6 (0.62) | HDAC6FAAHELANEPIK3CA | |
| SCHEMBL3477494 | 0.68 | FAAH (0.60) | HDAC6FAAHELANEPIK3CACDC7 | |
| SCHEMBL3477307 | 0.68 | FAAH (0.66) | HDAC6FAAHELANEPIK3CA | |
| SCHEMBL3475830 | 0.67 | FAAH (0.64) | HDAC6FAAHPIK3CA | |
| SCHEMBL3477409 | 0.67 | FAAH (0.71) | HDAC6FAAHELANEPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039186-A2 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |