Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9628106 | 0.81 | PPARD (0.56) | PPARGPPARDFFAR1 | |
| SCHEMBL3652699 | 0.80 | MTNR1A (0.54) | MTNR1A | |
| SCHEMBL132847 | 0.77 | MTNR1A (0.66) | HTR2CMTNR1A | |
| SCHEMBL172889 | 0.77 | HTR1A (0.57) | HTR1AHTR1DHTR2CMTNR1ACYP3A4 | |
| Methylamine SCHEMBL10700891 | 0.76 | HTR1A (0.50) | HTR1AHTR1DHTR2CMTNR1ACYP3A4 | |
| SCHEMBL136496 | 0.75 | MTNR1A (0.64) | MTNR1A | |
| SCHEMBL24090506 | 0.75 | HTR2B (0.55) | HTR1AMTNR1ACYP3A4HCRTR1HCRTR2 | |
| SCHEMBL138000 | 0.74 | MTNR1A (0.51) | MTNR1A | |
| SCHEMBL9628688 | 0.74 | HTR2B (0.43) | HTR1AHTR2CMTNR1ACYP3A4DRD2 | |
| SCHEMBL9627798 | 0.74 | HTR1A (0.50) | HTR1AHTR1DHTR2CMTNR1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120059053-A1 | COMPOUNDS OF 2,3-DIHYDRO-BENZOFURAN | FERRER INTERNATIONAL, S.A. (ES) | 2012-03-08 | — | — | US | claimed |
| US-20120059053-A1 | COMPOUNDS OF 2,3-DIHYDRO-BENZOFURAN | FERRER INTERNATIONAL, S.A. (ES) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059053-A1 | COMPOUNDS OF 2,3-DIHYDRO-BENZOFURAN | MTNR1A, MTNR1B, CRY2 | HTR1A 67/4885HTR1D 146/4885HTR2C 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.