SCHEMBL13491479

SCHEMBL13491479

O=C(NCc1cccc(Oc2ccccc2)c1)c1cc(F)c2ncccc2c1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 4/20 0.53
FFAR1 O14842 1/20 0.52
MAPK8 P45983 1/20 0.48
LMNA P02545 2/20 0.48
TP53 P04637 1/20 0.48
MAPT P10636 1/20 0.48
THRB P10828 1/20 0.48
PSMD14 O00487 1/20 0.47
COPS5 Q92905 1/20 0.47
MMP13 P45452 2/20 0.47
ALDH1A1 P00352 1/20 0.47
CYP3A4 P08684 1/20 0.47
HTT P42858 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
HPGD P15428 1/20 0.47
LOX P28300 2/20 0.46
LOXL2 Q9Y4K0 2/20 0.46
ROCK2 O75116 1/20 0.46
EGLN1 Q9GZT9 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13491408 0.88 ALDH1A1 (0.60) LMNAMAPTPSMD14COPS5ALDH1A1
SCHEMBL13491430 0.84 HDAC1 (0.52) LMNAMAPTPSMD14COPS5ALDH1A1
SCHEMBL5697540 0.83 PSMD14 (0.54) MAPK14FFAR1MAPK8LMNAPSMD14
SCHEMBL1681262 0.82 FFAR1 (0.57) MAPK14FFAR1MAPK8LMNAMMP13
SCHEMBL13491582 0.80 MAPK8 (0.54) MAPK14FFAR1MAPK8MAPTMMP13
SCHEMBL1680867 0.79 EGLN1 (0.55) MAPK14FFAR1LMNAMAPTMMP13
SCHEMBL13491323 0.78 LMNA (0.52) LMNAALDH1A1HPGDROCK2
SCHEMBL1680887 0.78 EGLN1 (0.56) MAPK14FFAR1LMNATP53MAPT
SCHEMBL13491480 0.77 EGLN1 (0.51) MAPK14FFAR1LMNAMAPTMMP13
SCHEMBL28042144 0.76 MAPK8 (0.51) MAPK14FFAR1MAPK8LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100041694-A1 AGRICULTURAL COMPOSITION FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENIC MICROBES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-02-18 US disclosed
US-20100041694-A1 AGRICULTURAL COMPOSITION FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENIC MICROBES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-02-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100041694-A1 AGRICULTURAL COMPOSITION FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENIC MICROBES HDHD5, NAAA, BROX MAPK14 2552/4885FFAR1 2005/4885MAPK8 3554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.