Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.41 |
| ▸ | MMP2 | P08253 | 5/20 | 0.35 |
| ▸ | MMP9 | P14780 | 5/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 3/20 | 0.34 |
| ▸ | MMP13 | P45452 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.31 |
| ▸ | FCER2 | P06734 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13535265 | 0.81 | KDM4E (0.43) | — | |
| SCHEMBL13535268 | 0.80 | MTNR1A (0.48) | MTNR1AMTNR1BMMP2MMP9MAOA | |
| SCHEMBL15713968 | 0.72 | CYP1A2 (0.53) | — | |
| SCHEMBL23190984 | 0.66 | MMP2 (0.56) | MTNR1AMTNR1BMMP2MMP9MAOA | |
| SCHEMBL14064539 | 0.64 | TRPA1 (0.41) | — | |
| SCHEMBL7367582 | 0.64 | MTNR1A (0.51) | MTNR1AMTNR1BMMP2MMP9MAOA | |
| SCHEMBL13659834 | 0.64 | MAOA (0.58) | MTNR1AMTNR1BMAOAMAOBCA1 | |
| SCHEMBL916141 | 0.64 | MAOA (0.56) | MTNR1AMTNR1BMAOAMAOBCA1 | |
| SCHEMBL7368245 | 0.63 | MTNR1A (0.59) | MTNR1AMTNR1BMMP2MMP9MAOA | |
| SCHEMBL13461656 | 0.63 | ALDH1A1 (0.46) | MTNR1AMTNR1BMAOAMAOBFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7649015-B2 | Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds | GILEAD SCIENCES, INC. (US) | 2010-01-19 | — | — | US | disclosed |