Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.68 |
| ▸ | HTT | P42858 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9593014 | 0.88 | HTR6 (0.61) | HTR6HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL9591962 | 0.85 | HTR6 (0.58) | HTR6HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL2509437 | 0.83 | RAPGEF4 (0.67) | HTR6HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL429849 | 0.82 | HTR6 (1.00) | HTR6HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL29558135 | 0.82 | HTR6 (1.00) | HTR6HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL27642789 | 0.81 | HTR6 (0.60) | HTR6HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL1973635 | 0.81 | HTR6 (0.69) | HTR6HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL27830593 | 0.81 | PPARG (0.57) | HTR6ALDH1A1AKR1C3AKR1C1PPARG | |
| Hydrochloric Acid SCHEMBL28794299 | 0.80 | HTR6 (0.96) | HTR6HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL6350593 | 0.79 | PPARG (0.69) | AKR1C3AKR1C1PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318725-B2 | Aryl indolyl sulfonamide compounds and their use as 5-HT6 ligands | SUVEN LIFE SCIENCES LIMITED (IN) | 2012-11-27 | — | — | US | disclosed |
| US-20110281849-A1 | Aryl Indolyl Sulfonamide Compounds and Their Use as 5-HT6 Ligands | SUVEN LIFE SCIENCES LIMITED (IN) | 2011-11-17 | — | — | US | disclosed |
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | HTR6 4311/4885HTT 2677/4885MEN1 3274/4885 |
| US-20110281849-A1 | Aryl Indolyl Sulfonamide Compounds and Their Use as 5-HT6 Ligands | HTR6, HTR1A, HTR2C | HTR6 1/4885HTT 157/4885MEN1 2762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.