SCHEMBL13554138

SCHEMBL13554138

c1ccc(-c2cc(-c3ccc4c(c3)c3ccccc3n4-c3ccccc3)nc(-c3ccccc3)n2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.51
ATM Q13315 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
KMT2A Q03164 8/20 0.47
MEN1 O00255 7/20 0.47
HPGD P15428 6/20 0.47
ALDH1A1 P00352 5/20 0.47
MAPT P10636 5/20 0.47
NTSR1 P30989 1/20 0.47
LMNA P02545 2/20 0.46
GLA P06280 1/20 0.46
PTGER4 P35408 1/20 0.42
ADORA2A P29274 2/20 0.41
ADORA1 P30542 2/20 0.41
NPSR1 Q6W5P4 1/20 0.40
RXFP1 Q9HBX9 1/20 0.40
CYP2C19 P33261 1/20 0.40
MAOA P21397 2/20 0.39
MAOB P27338 2/20 0.39
MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20251576 0.99 KDM4E (0.50) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL13554137 0.99 KDM4E (0.53) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL15395012 0.97 KDM4E (0.51) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL15394914 0.97 KDM4E (0.51) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL20251551 0.96 KDM4E (0.47) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL20251557 0.96 KDM4E (0.47) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL24725269 0.96 KDM4E (0.50) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL6375087 0.96 KDM4E (0.50) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL15371722 0.96 KDM4E (0.50) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL15371730 0.96 KDM4E (0.50) KDM4EATML3MBTL1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230189544-A1 LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-15 US disclosed
US-20230189544-A1 LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-15 US disclosed
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2022-12-29 US disclosed
US-10822330-B2 Heterocyclic compound and organic light emitting diode containing same LG CHEM, LTD. (KR) 2020-11-03 US disclosed
US-10651411-B2 Compound and organic light emitting device containing same LG CHEM, LTD. (KR) 2020-05-12 US disclosed
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME LG CHEM, LTD. (KR) 2018-05-24 US disclosed
US-20120267620-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE, ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME, AND DISPLAY DEVICE INCLUDING THE ORGANIC PHOTOELECTRIC DEVICE CHEIL INDUSTRIES, INC. (KR) 2012-10-25 US disclosed
US-20120267620-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE, ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME, AND DISPLAY DEVICE INCLUDING THE ORGANIC PHOTOELECTRIC DEVICE CHEIL INDUSTRIES, INC. (KR) 2012-10-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS PIEZO1, TMEM109, SLC39A14 KDM4E 3416/4885ATM 3436/4885L3MBTL1 1876/4885
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME CRY1, CRY2, OR10J3 KDM4E 1258/4885ATM 2781/4885L3MBTL1 349/4885
US-20120267620-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE, ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME, AND DISPLAY DEVICE INCLUDING THE ORGANIC PHOTOELECTRIC DEVICE PPOX, AOX1, PNPO KDM4E 1649/4885ATM 3669/4885L3MBTL1 4094/4885
US-10651411-B2 Compound and organic light emitting device containing same CRY1, CRY2, OR10J3 KDM4E 1258/4885ATM 2781/4885L3MBTL1 349/4885
US-10822330-B2 Heterocyclic compound and organic light emitting diode containing same CRY1, CRY2, PER2 KDM4E 2233/4885ATM 3624/4885L3MBTL1 895/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.