Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
| ▸ | RXRG | P48443 | 1/20 | 0.30 |
| ▸ | SOD1 | P00441 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15332805 | 0.83 | MGLL (0.39) | MGLLRXRARXRBRXRGSOD1 | |
| SCHEMBL12260219 | 0.77 | RXRA (0.47) | MGLLRXRARXRBRXRGSOD1 | |
| SCHEMBL29950784 | 0.77 | RXRA (0.47) | MGLLRXRARXRBRXRGSOD1 | |
| SCHEMBL29951977 | 0.75 | MGLL (0.41) | MGLLRXRARXRBRXRGSOD1 | |
| SCHEMBL15330176 | 0.74 | MGLL (0.43) | MGLLRXRARXRBRXRG | |
| SCHEMBL29955738 | 0.73 | FAAH (0.42) | MGLLRXRARXRBRXRG | |
| SCHEMBL13554239 | 0.73 | RXRA (0.33) | MGLLRXRARXRBRXRG | |
| SCHEMBL1409616 | 0.72 | ENPP2 (0.47) | MGLLRXRARXRBRXRG | |
| SCHEMBL29954385 | 0.71 | MGLL (0.43) | MGLL | |
| SCHEMBL15329420 | 0.70 | MGLL (0.42) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120270838-A1 | SPIROIMIDAZOLONE DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2012-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120270838-A1 | SPIROIMIDAZOLONE DERIVATIVE | WNK3, REN, SGK3 | MGLL 4716/4885RXRA 2610/4885RXRB 2718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.