Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 6/20 | 0.81 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.81 |
| ▸ | LMNA | P02545 | 3/20 | 0.81 |
| ▸ | DRD3 | P35462 | 3/20 | 0.81 |
| ▸ | HTR2A | P28223 | 2/20 | 0.81 |
| ▸ | HTR2B | P41595 | 2/20 | 0.81 |
| ▸ | BLM | P54132 | 2/20 | 0.81 |
| ▸ | CNR1 | P21554 | 1/20 | 0.81 |
| ▸ | APEX1 | P27695 | 1/20 | 0.81 |
| ▸ | PDE4A | P27815 | 1/20 | 0.81 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.81 |
| ▸ | DRD2 | P14416 | 2/20 | 0.80 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.80 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.80 |
| ▸ | CYP2J2 | P51589 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.68 |
| ▸ | GMNN | O75496 | 1/20 | 0.68 |
| ▸ | USP2 | O75604 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16345651 | 1.00 | HRH1 (0.81) | HRH1KCNH2LMNADRD3HTR2A | |
| Hydrochloric Acid SCHEMBL13516884 | 0.99 | HRH1 (0.82) | HRH1KCNH2LMNADRD3HTR2A | |
| Fexofenadine SCHEMBL4900 | 0.90 | HRH1 (1.00) | HRH1KCNH2LMNADRD3HTR2A | |
| Fexofenadine SCHEMBL7104316 | 0.90 | HRH1 (1.00) | HRH1KCNH2LMNADRD3HTR2A | |
| Fexofenadine SCHEMBL1561082 | 0.90 | HRH1 (1.00) | HRH1KCNH2LMNADRD3HTR2A | |
| Fexofenadine SCHEMBL4901 | 0.90 | HRH1 (1.00) | HRH1KCNH2LMNADRD3HTR2A | |
| Fexofenadine SCHEMBL1972366 | 0.90 | HRH1 (1.00) | HRH1KCNH2LMNADRD3HTR2A | |
| Fexofenadine SCHEMBL3178320 | 0.90 | HRH1 (1.00) | HRH1KCNH2LMNADRD3HTR2A | |
| Fexofenadine SCHEMBL16652201 | 0.89 | HRH1 (0.98) | HRH1KCNH2LMNADRD3HTR2A | |
| Fexofenadine SCHEMBL9943442 | 0.89 | HRH1 (0.98) | HRH1KCNH2LMNADRD3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10130620-B2 | Liquid pharmaceutical composition for oral administration comprising fexofenadine | AVENTISUB LLC (US) | 2018-11-20 | — | — | US | disclosed |
| US-20160184284-A1 | LIQUID PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION COMPRISING FEXOFENADINE | CHATTEM, INC. | 2016-06-30 | — | — | US | disclosed |
| EP-3016635-A1 | LIQUID PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION COMPRISING FEXOFENADINE | Aventisub LLC (US) | 2016-05-11 | — | — | EP | disclosed |
| WO-2015001478-A1 | LIQUID PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION COMPRISING FEXOFENADINE | AVENTIS PHARMACEUTICALS INC. (US) | 2015-01-08 | — | — | WO | disclosed |
| EP-2532644-A1 | Preparation of 2-(4-bromophenyl)-2-methylpropanoic acid | Divi's Laboratories Limited (IN) | 2012-12-12 | — | — | EP | disclosed |
| US-20120309973-A1 | PREPARATION OF 2-(4-BROMOPHENYL)-2-METHYLPROPANOIC ACID | DIVI'S LABORATORIES LIMITED (IN) | 2012-12-06 | — | — | US | disclosed |
| US-20120276199-A1 | TASTE MASKED PHARMACEUTICAL FORMULATIONS | DR. REDDY'S LABORATORIES LIMITED (IN) | 2012-11-01 | — | — | US | disclosed |
| US-20120276199-A1 | TASTE MASKED PHARMACEUTICAL FORMULATIONS | DR. REDDY'S LABORATORIES LIMITED (IN) | 2012-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120309973-A1 | PREPARATION OF 2-(4-BROMOPHENYL)-2-METHYLPROPANOIC ACID | HRH2, NPFFR2, GABRA6 | HRH1 26/4885KCNH2 371/4885LMNA 4153/4885 |
| US-20160184284-A1 | LIQUID PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION COMPRISING FEXOFENADINE | SORD, SFXN1, SLC10A2 | HRH1 88/4885KCNH2 1049/4885LMNA 4217/4885 |
| US-10130620-B2 | Liquid pharmaceutical composition for oral administration comprising fexofenadine | SORD, SFXN1, SLC10A2 | HRH1 88/4885KCNH2 1049/4885LMNA 4217/4885 |
| US-20120276199-A1 | TASTE MASKED PHARMACEUTICAL FORMULATIONS | TAS2R5, TAS2R20, TAS1R2 | HRH1 52/4885KCNH2 212/4885LMNA 4193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.