SCHEMBL13565701

SCHEMBL13565701

C/C=C/CSc1cccc(SCCCCCC2CCC(NS(=O)(=O)C(C)(C)C)CC2)c1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.31
NPY5R Q15761 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17090152 0.88 NPY5R (0.32) CNR2NPY5R
SCHEMBL10114202 0.83 NPY5R (0.40) CNR2NPY5R
SCHEMBL13100671 0.80 ALDH1A1 (0.36)
SCHEMBL11935187 0.68 DRD2 (0.33)
SCHEMBL13565737 0.67 OPRM1 (0.37) NPY5R
SCHEMBL10114192 0.64 NPY5R (0.41) NPY5R
SCHEMBL13565685 0.63 MTNR1A (0.37)
SCHEMBL17090307 0.61 THRB (0.42) CNR2
SCHEMBL13565621 0.61 THRB (0.42) CNR2
SCHEMBL13565448 0.61 SMYD3 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8299265-B2 Amine derivatives having NPY Y5 receptor antagonistic activity and the uses thereof SHIONOGI & CO., LTD. (JP) 2012-10-30 US disclosed