Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565701 | 0.88 | CNR2 (0.31) | NPY5RCNR2 | |
| SCHEMBL10114202 | 0.86 | NPY5R (0.40) | NPY5RL3MBTL1CNR2 | |
| SCHEMBL11935187 | 0.81 | DRD2 (0.33) | FDPS | |
| SCHEMBL13565737 | 0.77 | OPRM1 (0.37) | NPY5R | |
| SCHEMBL13565448 | 0.73 | SMYD3 (0.38) | — | |
| SCHEMBL13565685 | 0.73 | MTNR1A (0.37) | — | |
| SCHEMBL13565454 | 0.72 | LMNA (0.38) | NPY5R | |
| SCHEMBL13565739 | 0.70 | NPC1 (0.33) | NPY5RL3MBTL1CNR2 | |
| SCHEMBL13564844 | 0.70 | ALDH1A1 (0.43) | L3MBTL1CNR2 | |
| SCHEMBL13564861 | 0.70 | POLB (0.44) | FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |