SCHEMBL1358509

SCHEMBL1358509

Clc1ccc2[nH]c(C(Cl)(Cl)Cl)nc2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HRH4 Q9H3N8 3/20 0.41
▸ F7 P08709 2/20 0.41
▸ F3 P13726 2/20 0.41
▸ AHR P35869 2/20 0.41
▸ LTA4H P09960 1/20 0.41
▸ NR4A2 P43354 1/20 0.41
▸ ALDH1A1 P00352 3/20 0.41
▸ HTR3E A5X5Y0 1/20 0.41
▸ HTR3B O95264 1/20 0.41
▸ HTR3A P46098 1/20 0.41
▸ BACE1 P56817 1/20 0.41
▸ HTR3D Q70Z44 1/20 0.41
▸ HTR3C Q8WXA8 1/20 0.41
▸ NOS1 P29475 1/20 0.39
▸ DYRK1A Q13627 1/20 0.38
▸ NPSR1 Q6W5P4 1/20 0.38
▸ F11 P03951 1/20 0.38
▸ PIK3CG P48736 1/20 0.38
▸ HPGD P15428 3/20 0.38
▸ PSMB8 P28062 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1358510 0.85 ALDH1A1 (0.58) ALDH1A1HTR3EHTR3BHTR3ABACE1
SCHEMBL10248397 0.84 SMN1; SMN2 (0.45) HRH4F7F3AHRLTA4H
SCHEMBL9866407 0.84 NPSR1 (0.58) HRH4F7F3AHRLTA4H
SCHEMBL5110913 0.81 SCN10A (0.54) HRH4F7F3AHRLTA4H
SCHEMBL2241014 0.80 NPSR1 (0.41) AHRALDH1A1NPSR1HPGDSMN1; SMN2
SCHEMBL4349193 0.80 KMT2A (0.41) ALDH1A1NPSR1HPGDHSD17B10POLB
SCHEMBL5773139 0.80 NOS1 (0.38) ALDH1A1NOS1DYRK1ANPSR1HPGD
SCHEMBL1509452 0.80 NOS1 (0.38) AHRNR4A2ALDH1A1BACE1NOS1
SCHEMBL11343558 0.78 ALDH1A1 (0.44) NR4A2ALDH1A1SMN1; SMN2TDP1POLB
SCHEMBL2361268 0.77 NPSR1 (0.46) ALDH1A1NPSR1HPGDSMN1; SMN2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0251760-B1 Rubber composition BRIDGESTONE CORP (JP) 1994-01-26 — — EP claimed
US-5140055-A Improved high speed grip performance BRIDGESTONE CORPORATION (JP) 1992-08-18 — — US claimed
EP-0128563-B1 IMPROVED ANTIFOGGANT PROCESS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-04-04 — — EP claimed
EP-0128563-A2 Improved antifoggant process E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-12-19 — — EP claimed
US-4468454-A NEGATIVE SILVER HALIDE EMULSIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-08-28 — — US claimed
EP-0045570-B1 USE OF ORGANIC HALOGEN COMPOUNDS TO REDUCE OR PREVENT FOG IN NEGATIVE-WORKING SILVER HALIDE EMULSIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-09-28 — — EP claimed
US-4323645-A Organic halogen compounds for negative-working silver halide emulsions E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-04-06 — — US claimed
EP-0045570-A1 Use of organic halogen compounds to reduce or prevent fog in negative-working silver halide emulsions E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-02-10 — — EP claimed
US-20260138071-A1 SULFIDE GAS REMOVAL PROCESS KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2026-05-21 — — US disclosed
US-20260014517-A1 HYDROGEN SULFIDE REMOVAL METHOD FROM DRILLING MUD COMPOSITION KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2026-01-15 — — US disclosed
US-20260014197-A1 DRUG DELIVERY SYSTEM IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2026-01-15 — — US disclosed
US-20260014514-A1 METHOD FOR SCAVENGING HYDROGEN SULFIDE FROM A GASEOUS COMPOSITION IN A STIRRED TANK REACTOR KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2026-01-15 — — US disclosed
US-20260008009-A1 PROCESS FOR REMOVING HYDROGEN SULFIDE FROM A HYDROCARBON GASEOUS COMPOSITION KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2026-01-08 — — US disclosed
US-20260002088-A1 PROCESS TO REMOVE HYDROGEN SULFIDE FROM A HYDROCARBON-CONTAINING GAS COMPOSITION KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2026-01-01 — — US disclosed
EP-0251760-B1 Rubber composition BRIDGESTONE CORP (JP) 1994-01-26 — — EP disclosed
EP-0128563-A2 Improved antifoggant process E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-12-19 — — EP disclosed
US-4468454-A NEGATIVE SILVER HALIDE EMULSIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-08-28 — — US disclosed
EP-0045570-B1 USE OF ORGANIC HALOGEN COMPOUNDS TO REDUCE OR PREVENT FOG IN NEGATIVE-WORKING SILVER HALIDE EMULSIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-09-28 — — EP disclosed
US-4323645-A Organic halogen compounds for negative-working silver halide emulsions E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-04-06 — — US disclosed
EP-0045570-A1 Use of organic halogen compounds to reduce or prevent fog in negative-working silver halide emulsions E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-02-10 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008009-A1 PROCESS FOR REMOVING HYDROGEN SULFIDE FROM A HYDROCARBON GASEOUS COMPOSITION HMOX2, HMOX1, SCO2 HRH4 16/4885F7 1330/4885F3 183/4885
US-20260014517-A1 HYDROGEN SULFIDE REMOVAL METHOD FROM DRILLING MUD COMPOSITION TST, SOD1, SAMM50 HRH4 1560/4885F7 2344/4885F3 2699/4885
US-20260002088-A1 PROCESS TO REMOVE HYDROGEN SULFIDE FROM A HYDROCARBON-CONTAINING GAS COMPOSITION SAMM50, SOD1, HNRNPH3 HRH4 18/4885F7 1248/4885F3 185/4885
US-20260138071-A1 SULFIDE GAS REMOVAL PROCESS SAMM50, SRSF1, GTF2F1 HRH4 200/4885F7 208/4885F3 36/4885
US-20260014514-A1 METHOD FOR SCAVENGING HYDROGEN SULFIDE FROM A GASEOUS COMPOSITION IN A STIRRED TANK REACTOR SOD1, MAFG, HMOX2 HRH4 477/4885F7 35/4885F3 643/4885
US-20260014197-A1 DRUG DELIVERY SYSTEM IPO8, SLC39A11, SLC2A8 HRH4 4133/4885F7 1563/4885F3 2725/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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