Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSPO | P30536 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6135895 | 0.90 | NPC1 (0.33) | NOTUMSMN1; SMN2NPC1RAB9A | |
| SCHEMBL17512909 | 0.81 | USP1 (0.37) | NOTUMSMN1; SMN2GAALMNAPOLB | |
| SCHEMBL10448205 | 0.81 | NPC1 (0.45) | NOTUMMAOBSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL135941 | 0.80 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1MAPTGAAHPGD | |
| SCHEMBL343082 | 0.77 | DAPK3 (0.40) | NOTUMMAOBDAPK3 | |
| SCHEMBL9360045 | 0.77 | ALDH1A1 (0.38) | MAOBALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6699746 | 0.74 | NPC1 (0.35) | SMN1; SMN2ALDH1A1MAPTGAAHPGD | |
| SCHEMBL341526 | 0.74 | LMNA (0.43) | MAOBGAAMEN1KMT2ALMNA | |
| SCHEMBL6699179 | 0.73 | TSHR (0.35) | — | |
| SCHEMBL15968776 | 0.73 | KMO (0.44) | ALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646291-A | CONTACTING ACETIC ANHYDRIDE, A HIPPURIC ACID, A WATER CONTAINING ACIDIC SOLUTION OF A BENZENEDIAZONIUM SALT AND A NEUTRALIZING AGENT UNDER CYCLOCONDENSATION CONDITIONS | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-07-08 | — | — | US | disclosed |
| US-5541080-A | SOLVOLYSIS WITH METHANOL IN PRESENCE OF A LIPASE IN NON-POLAR SOLVENT FOLLOWED BY ENANTIOSELECTIVELY CLEAVING ESTER WITH A PROTEASE | WISCONSIN ALUMNI RESEARCH FDN. (US) | 1996-07-30 | — | — | US | disclosed |