Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.55 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.55 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.55 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.55 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.55 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2925616 | 0.89 | MEN1 (0.60) | MEN1KMT2APOLBCYP2C9CYP2C19 | |
| SCHEMBL21614171 | 0.88 | MEN1 (0.53) | MEN1KMT2APOLBGRIN2DGRIN3B | |
| SCHEMBL19994627 | 0.87 | MEN1 (0.55) | MEN1KMT2APOLBCYP2C9CYP2C19 | |
| SCHEMBL14559864 | 0.86 | MEN1 (0.56) | MEN1KMT2APOLBCYP2C9CYP2C19 | |
| SCHEMBL4576736 | 0.85 | L3MBTL1 (0.69) | MEN1KMT2AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL16600135 | 0.84 | MEN1 (0.55) | MEN1KMT2APOLBGRIN2DGRIN3B | |
| SCHEMBL1761030 | 0.84 | MEN1 (0.55) | MEN1KMT2APOLBCYP2C9CYP2C19 | |
| SCHEMBL4578422 | 0.84 | ALDH1A1 (0.57) | MEN1KMT2AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL5806708 | 0.84 | MEN1 (0.55) | MEN1KMT2APOLBGRIN2DGRIN3B | |
| SCHEMBL4576966 | 0.84 | FAAH (0.61) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260053786-A1 | FORMULATIONS OF RADIPRODIL | GRIN THERAPEUTICS INC (US) | 2026-02-26 | — | — | US | disclosed |
| US-12419881-B1 | Methods of using radiprodil in the treatment of disorders | GRIN THERAPEUTICS, INC. (US) | 2025-09-23 | — | — | US | disclosed |
| US-20250288574-A1 | METHODS OF USING RADIPRODIL IN THE TREATMENT OF DISORDERS | GRIN THERAPEUTICS, INC. | 2025-09-18 | — | — | US | disclosed |
| US-20250288518-A1 | METHODS OF USING RADIPRODIL IN THE TREATMENT OF DISORDERS | GRIN THERAPEUTICS, INC. | 2025-09-18 | — | — | US | disclosed |
| US-20250127770-A1 | FORMULATIONS OF RADIPRODIL | GRIN THERAPEUTICS, INC. | 2025-04-24 | — | — | US | disclosed |
| US-20120059034-A1 | NOVEL CRYSTALLINE HYDRATE, AMORPHOUS AND POLYMORPHIC FORMS OF DIHYDRO-BENZOXAZOLE-6-YL-ACETAMIDE DERIVATIVE AND PROCESSES FOR THEIR PREPARATION | RICHTER GEDEON NYRT. (HU) | 2012-03-08 | — | — | US | disclosed |
| EP-2403850-A1 | NOVEL CRYSTALLINE HYDRATE, AMORPHOUS AND POLYMORPHIC FORMS OF DIHYDRO-BENZOXAZOLE-6-YL-ACETAMIDE DERIVATIVE AND PROCESSES FOR THEIR PREPARATION | Richter Gedeon Nyrt. (HU) | 2012-01-11 | — | — | EP | disclosed |
| EP-2303014-A1 | NOVEL CRYSTALLINE FORM OF 2-Ý4(4-FLUORO-BENZYL)-PIPERIDINE-1-YL¨-2-OXO-N-(2-OXO-2,3-DIHYDRO-BENZOXAZOL-6-YL)-ACETAMIDE | Richter Gedeon Nyrt. (HU) | 2011-04-06 | — | — | EP | disclosed |
| WO-2010100512-A1 | NOVEL CRYSTALLINE HYDRATE, AMORPHOUS AND POLYMORPHIC FORMS OF DIHYDRO-BENZOXAZOLE-6-YL-ACETAMIDE DERIVATIVE AND PROCESSES FOR THEM PREPARATION | RICHTER GEDEON NYRT. (HU) | 2010-09-10 | — | — | WO | disclosed |
| US-20100010044-A1 | NOVEL CRYSTALLINE FORM OF 2-[4-(4-FLUORO-BENZYL)-PIPERIDINE-1-YL]-2-OXO-N-(2-OXO-2,3-DIHYDRO-BENZOXAZOL-6-YL)-ACETAMIDE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-01-14 | — | — | US | disclosed |
| WO-2010006020-A1 | NOVEL CRYSTALLINE FORM OF 2-[4(4-FLUORO-BENZYL)-PIPERIDINE-1-YL]-2-OXO-N-(2-OXO-2,3-DIHYDRO-BENZOXAZOL-6-YL)-ACETAMIDE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-01-14 | — | — | WO | disclosed |
| US-7435744-B2 | Piperidine derivatives as NMDA receptor antagonists | GEDEON RICHTER VEGYESZETI GYAR RT (HU) | 2008-10-14 | — | — | US | disclosed |
| EP-1409477-B1 | PIPERIDINE DERIVATIVES AS NMDA RECEPTOR ANTAGONISTS | RICHTER GEDEON NYRT (HU) | 2008-09-17 | — | — | EP | disclosed |
| CN-100413860-C | piperidine derivatives as NMDA receptor antagonists | HUNGARY GIREL GYOGYSZERGYAR (HU) | 2008-08-27 | — | — | CN | disclosed |
| CN-1556805-A | piperidine derivatives as NMDA receptor antagonists | ������ҩ������˾ | 2004-12-22 | — | — | CN | disclosed |
| US-20040157886-A1 | Piperdine derivatives as NMDA receptor antagonists | UCB Biopharma SRL (BE) | 2004-08-12 | — | — | US | disclosed |
| EP-1409477-A1 | PIPERIDINE DERIVATIVES AS NMDA RECEPTOR ANTAGONISTS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003010159-A1 | PIPERIDINE DERIVATIVES AS NMDA RECEPTOR ANTAGONISTS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2003-02-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260053786-A1 | FORMULATIONS OF RADIPRODIL | GRIN2D, GRIN2A, GRIN2B | MEN1 2042/4885KMT2A 1298/4885POLB 4671/4885 |
| US-20040157886-A1 | Piperdine derivatives as NMDA receptor antagonists | GRIN1, GRIN2D, GRIN2C | MEN1 2584/4885KMT2A 1234/4885POLB 3167/4885 |
| US-20250288574-A1 | METHODS OF USING RADIPRODIL IN THE TREATMENT OF DISORDERS | CLN6, GABARAPL2, GABARAPL1 | MEN1 1864/4885KMT2A 3960/4885POLB 1720/4885 |
| US-20100010044-A1 | NOVEL CRYSTALLINE FORM OF 2-[4-(4-FLUORO-BENZYL)-PIPERIDINE-1-YL]-2-OXO-N-(2-OXO-2,3-DIHYDRO-BENZOXAZOL-6-YL)-ACETAMIDE | UACA, CANX, AQP4 | MEN1 4351/4885KMT2A 1130/4885POLB 2533/4885 |
| US-12419881-B1 | Methods of using radiprodil in the treatment of disorders | CLN6, GABARAPL2, GABARAPL1 | MEN1 1864/4885KMT2A 3960/4885POLB 1720/4885 |
| US-20120059034-A1 | NOVEL CRYSTALLINE HYDRATE, AMORPHOUS AND POLYMORPHIC FORMS OF DIHYDRO-BENZOXAZOLE-6-YL-ACETAMIDE DERIVATIVE AND PROCESSES FOR THEIR PREPARATION | DHX35, DHX9, ABCG2 | MEN1 4684/4885KMT2A 3952/4885POLB 2702/4885 |
| US-20250288518-A1 | METHODS OF USING RADIPRODIL IN THE TREATMENT OF DISORDERS | CLN6, GABARAPL2, GABARAPL1 | MEN1 1864/4885KMT2A 3960/4885POLB 1720/4885 |
| US-20250127770-A1 | FORMULATIONS OF RADIPRODIL | GABARAPL2, PARL, GABARAPL1 | MEN1 2922/4885KMT2A 4623/4885POLB 2527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.