Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6659536 | 0.70 | CHRNB2 (0.49) | ALDH1A1MAPTCYP2D6KMT2AMEN1 | |
| SCHEMBL6752686 | 0.68 | OPRM1 (0.42) | ALDH1A1MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12143873 | 0.68 | ALDH1A1 (0.52) | ALDH1A1KMT2ASMN1; SMN2OPRM1OPRD1 | |
| SCHEMBL6662488 | 0.68 | ALDH1A1 (0.43) | ALDH1A1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5821067 | 0.68 | ALDH1A1 (0.41) | ALDH1A1MAPTHPGDCYP1A2CYP3A4 | |
| SCHEMBL30000702 | 0.67 | ALDH1A1 (0.41) | ALDH1A1MAPTKMT2ASMN1; SMN2TP53 | |
| SCHEMBL4339044 | 0.66 | PTPRC (0.41) | ALDH1A1MAPTCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL23409273 | 0.64 | KMT2A (0.50) | ALDH1A1MAPTCYP1A2CYP2C19KMT2A | |
| SCHEMBL23111942 | 0.64 | KMT2A (0.50) | ALDH1A1MAPTCYP1A2CYP2C19KMT2A | |
| SCHEMBL1836941 | 0.63 | KMT2A (0.48) | ALDH1A1HPGDKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612197-B2 | Reacting a nucleophil with OH group with an electrophil to form an adduct, reacting adduct with a reagent selected from oxidizing, sulfurizing or selenizing agents to produce hydroxy protected oligonucleotide, heating to deprotect hydroxy protecting group such as 2-(2-pyridyl)aminoethoxycarbonyl | The United States of America as repesented by the Secretary of the Department of Health and Human Services (US) | 2009-11-03 | — | — | US | disclosed |