Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6659536 | 0.80 | CHRNB2 (0.49) | ALDH1A1MAPTHTTSMN1; SMN2LMNA | |
| SCHEMBL5821067 | 0.78 | ALDH1A1 (0.41) | ALDH1A1MAPTHTTSMN1; SMN2LMNA | |
| SCHEMBL30000702 | 0.74 | ALDH1A1 (0.41) | ALDH1A1MAPTHTTSMN1; SMN2LMNA | |
| SCHEMBL6417963 | 0.70 | ALDH1A1 (0.51) | ALDH1A1MAPTKDM4EHTTSMN1; SMN2 | |
| SCHEMBL6659859 | 0.69 | ALDH1A1 (0.47) | ALDH1A1MAPTKDM4EHTTSMN1; SMN2 | |
| SCHEMBL6752686 | 0.69 | OPRM1 (0.42) | ALDH1A1MAPTHTTSMN1; SMN2LMNA | |
| SCHEMBL13613864 | 0.68 | ALDH1A1 (0.40) | ALDH1A1MAPTKDM4EHTTSMN1; SMN2 | |
| SCHEMBL4339044 | 0.68 | PTPRC (0.41) | ALDH1A1MAPTSMN1; SMN2LMNAGAA | |
| SCHEMBL30945319 | 0.66 | TSHR (0.48) | ALDH1A1MAPTHTTLMNATSHR | |
| SCHEMBL5313485 | 0.66 | ALDH1A1 (0.47) | ALDH1A1MAPTHTTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004004715-A2 | NOVEL DELTA OPIOID RECEPTOR LIGANDS | GLAXOSMITHKLINE SPA (IT) | 2004-01-15 | — | — | WO | claimed |
| WO-2004004715-A2 | NOVEL DELTA OPIOID RECEPTOR LIGANDS | GLAXOSMITHKLINE SPA (IT) | 2004-01-15 | — | — | WO | disclosed |