Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6662488 | 0.80 | ALDH1A1 (0.43) | CHRNB2CHRNA4DRD3MAPTALDH1A1 | |
| SCHEMBL6656820 | 0.74 | DRD2 (0.54) | DRD2DRD4DRD3MAPTALDH1A1 | |
| SCHEMBL6661644 | 0.73 | DRD2 (0.50) | DRD2DRD4DRD3MAPTALDH1A1 | |
| SCHEMBL5821067 | 0.72 | ALDH1A1 (0.41) | MAPTALDH1A1MAPK1SMN1; SMN2KMT2A | |
| SCHEMBL7038466 | 0.71 | CHRNB2 (0.86) | CHRNB2CHRNA4MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL13613864 | 0.70 | ALDH1A1 (0.40) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6662302 | 0.69 | MAPT (0.46) | DRD2DRD4DRD3MAPTALDH1A1 | |
| SCHEMBL3977089 | 0.69 | CHRNB2 (0.64) | CHRNB2CHRNA4DRD2DRD4DRD3 | |
| SCHEMBL6752686 | 0.68 | OPRM1 (0.42) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6661589 | 0.68 | LTA4H (0.41) | DRD2DRD4DRD3MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004004715-A2 | NOVEL DELTA OPIOID RECEPTOR LIGANDS | GLAXOSMITHKLINE SPA (IT) | 2004-01-15 | — | — | WO | disclosed |