Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5821067 | 0.75 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPTSMN1; SMN2RAB9A | |
| SCHEMBL30000702 | 0.72 | ALDH1A1 (0.41) | ATMALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL6752686 | 0.71 | OPRM1 (0.42) | ALDH1A1LMNAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL6662488 | 0.68 | ALDH1A1 (0.43) | ATMALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL6659536 | 0.68 | CHRNB2 (0.49) | ALDH1A1LMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL17687431 | 0.66 | PTPRC (0.63) | PTPRCALDH1A1LMNAMAPTSMN1; SMN2 | |
| Nitrobenzene SCHEMBL28227021 | 0.64 | ALDH1A1 (0.73) | PTPRCATMCYP19A1ALDH1A1LMNA | |
| SCHEMBL2633543 | 0.64 | PTPRC (0.69) | PTPRCALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL6302889 | 0.64 | PTPRC (0.69) | PTPRCALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL18000477 | 0.63 | TSHR (0.47) | ALDH1A1LMNAMAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612197-B2 | Reacting a nucleophil with OH group with an electrophil to form an adduct, reacting adduct with a reagent selected from oxidizing, sulfurizing or selenizing agents to produce hydroxy protected oligonucleotide, heating to deprotect hydroxy protecting group such as 2-(2-pyridyl)aminoethoxycarbonyl | The United States of America as repesented by the Secretary of the Department of Health and Human Services (US) | 2009-11-03 | — | — | US | disclosed |
| US-20060281911-A1 | Thermolabile hydroxyl protecting groups and methods of use | GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH (US) | 2006-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060281911-A1 | Thermolabile hydroxyl protecting groups and methods of use | ADH1A, CYP2E1, ADH1C | PTPRC 3601/4885ATM 3886/4885CYP19A1 116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.