Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | FABP3 | P05413 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.36 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.36 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.36 |
| ▸ | PYGL | P06737 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3060819 | 0.81 | CXCL8 (0.46) | LMNAMAPK1SLC22A12FABP4TSHR | |
| SCHEMBL23301921 | 0.78 | CES2 (0.50) | LMNAMAPK1FABP4FABP5TSHR | |
| SCHEMBL29723941 | 0.78 | CES2 (0.50) | LMNAMAPK1FABP4FABP5TSHR | |
| SCHEMBL3048207 | 0.77 | PDK1 (0.39) | LMNAMAPK1FABP4TSHRAKR1B1 | |
| 1,2-Dichlorobenzene SCHEMBL27641832 | 0.76 | FABP4 (0.46) | LMNAMAPK1FABP4FABP5ALDH1A1 | |
| SCHEMBL19979060 | 0.76 | ALDH1A1 (0.37) | LMNATSHRALDH1A1HDAC4CXCL8 | |
| SCHEMBL16494895 | 0.76 | FABP4 (0.58) | FABP4FABP5HPGD | |
| SCHEMBL9716063 | 0.76 | CPN1 (0.43) | LMNAAKR1B1PTGS2ITGB1ITGA4 | |
| SCHEMBL8854194 | 0.74 | LMNA (0.41) | LMNAMAPK1FABP4FABP5ALDH1A1 | |
| SCHEMBL23972669 | 0.74 | FABP4 (0.47) | LMNAMAPK1SLC22A12FABP4FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1197799-B1 | Silver halide photographic light-sensitive material comprising a yellow dye-forming coupler, and method for producing a yellow azomethine dye | FUJIFILM CORP (JP) | 2009-11-11 | — | — | EP | disclosed |