Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 6/20 | 0.33 |
| ▸ | NPC1 | O15118 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 3/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13622393 | 0.88 | GSK3B (0.39) | LMNAHPGD | |
| SCHEMBL13622908 | 0.80 | LMNA (0.41) | SMN1; SMN2LMNARAB9ANPC1KMT2A | |
| SCHEMBL13622324 | 0.73 | NNMT (0.33) | KMT2AKDM4EMEN1 | |
| SCHEMBL13256628 | 0.73 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL13622603 | 0.71 | TUBB4A (0.44) | SMN1; SMN2LMNARAB9ANPC1ALDH1A1 | |
| SCHEMBL13256629 | 0.69 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL13622400 | 0.69 | ATAD2 (0.34) | NPC1ALDH1A1KMT2APOLBGAA | |
| SCHEMBL2511414 | 0.66 | DAO (0.55) | SMN1; SMN2TAS1R3TAS1R1DAONAMPT | |
| SCHEMBL13622361 | 0.66 | ALDH1A1 (0.39) | SMN1; SMN2RAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL12786330 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009138712-A2 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-11-19 | — | — | WO | disclosed |