Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13622389 | 0.88 | SMN1; SMN2 (0.37) | HPGDLMNA | |
| SCHEMBL13622908 | 0.80 | LMNA (0.41) | GSK3BHPGDLMNA | |
| SCHEMBL13256628 | 0.73 | ALDH1A1 (0.35) | — | |
| SCHEMBL13622324 | 0.71 | NNMT (0.33) | — | |
| SCHEMBL13622603 | 0.71 | TUBB4A (0.44) | HDAC6HPGDLMNA | |
| SCHEMBL13256629 | 0.69 | ALDH1A1 (0.32) | — | |
| SCHEMBL13622400 | 0.67 | ATAD2 (0.34) | HPGDTSHR | |
| SCHEMBL13622361 | 0.66 | ALDH1A1 (0.39) | HPGD | |
| SCHEMBL12786330 | 0.66 | — | — | |
| SCHEMBL13622317 | 0.65 | ALDH1A1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009138712-A2 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-11-19 | — | — | WO | disclosed |