Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13628370 | 0.87 | NPC1 (0.44) | PDK4SYKNAMPTKMT2ACCR1 | |
| SCHEMBL13627814 | 0.82 | PPARG (0.41) | PDK4PPARGPPARASOS1MAPT | |
| SCHEMBL13627676 | 0.81 | CDK9 (0.37) | SYKSCN9AGRM5GRM1 | |
| SCHEMBL13627659 | 0.80 | CYP11B2 (0.38) | SOS1NAMPTCCR1SCN9A | |
| SCHEMBL13628658 | 0.78 | KMT2A (0.38) | SYKKMT2ACCR1SCN9AMAPK1 | |
| SCHEMBL13627813 | 0.78 | CCR2 (0.36) | PPARGPPARACCR1 | |
| SCHEMBL3326223 | 0.75 | PDK4 (0.65) | PDK4SOS1NAMPTHTR6GRM5 | |
| SCHEMBL13627810 | 0.72 | CCR1 (0.46) | SYKKMT2ACCR1MAPK1ATM | |
| SCHEMBL18901811 | 0.70 | PDK4 (0.43) | PDK4PPARGPPARAMAPTNAMPT | |
| SCHEMBL13334975 | 0.70 | CCR2 (0.51) | PDK4SOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7618970-B2 | 3-aminocyclopentanecarboxamides as modulators of chemokine receptors | INCYTE CORPORATION (US) | 2009-11-17 | — | — | US | disclosed |