Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16670594 | 0.82 | HDAC4 (0.62) | CSF1RHDAC4HDAC1ALDH1A1GAA | |
| SCHEMBL11805964 | 0.78 | ALDH1A1 (0.45) | CSF1RALDH1A1GAATSHRKDM4E | |
| SCHEMBL28611785 | 0.78 | ALDH1A1 (0.45) | CSF1RHDAC4HDAC1ALDH1A1GAA | |
| SCHEMBL29088436 | 0.78 | PRSS1 (0.49) | HDAC4HDAC1ALDH1A1PLK1TDP1 | |
| SCHEMBL22289272 | 0.78 | HPGD (0.49) | CSF1RALDH1A1TSHRKDM4EHTT | |
| SCHEMBL2324097 | 0.77 | HTT (0.55) | ALDH1A1GAATSHRKDM4EHTT | |
| SCHEMBL24595955 | 0.76 | HDAC4 (0.44) | HDAC4HDAC1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL6828818 | 0.76 | KLK7 (0.58) | CSF1RALDH1A1GAATSHRKDM4E | |
| SCHEMBL29088432 | 0.76 | HDAC4 (0.44) | HDAC4HDAC1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL28577903 | 0.76 | HTT (0.53) | ALDH1A1GAATSHRKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113543782-B | Pharmaceutical composition for preventing hair whitening and preventing or treating leukotrichia or vitiligo | 仁荷大学校产学协力团 | 2024-01-16 | — | — | CN | claimed |
| US-20220000832-A1 | Pharmaceutical Composition for Preventing Greying of Hair and Preventing or Treating Poliosis or Vitiligo | INHA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2022-01-06 | — | — | US | claimed |
| CN-113543782-A | Pharmaceutical composition for preventing hair from whitening and preventing or treating leukotrichia or vitiligo | 仁荷大学校产学协力团 | 2021-10-22 | — | — | CN | claimed |
| WO-2020159146-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING GREYING OF HAIR AND PREVENTING OR TREATING POLIOSISOR VITILIGO | 인하대학교 산학협력단 | 2020-08-06 | — | — | WO | claimed |
| US-12227482-B2 | Compounds and compositions for the treatment of cancer | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-02-18 | — | — | US | disclosed |
| EP-4339192-A2 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CANCER | The Regents of the University of California (US) | 2024-03-20 | — | — | EP | disclosed |
| CN-113543782-B | Pharmaceutical composition for preventing hair whitening and preventing or treating leukotrichia or vitiligo | 仁荷大学校产学协力团 | 2024-01-16 | — | — | CN | disclosed |
| EP-3478284-B1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CANCER | UNIV CALIFORNIA (US) | 2023-10-04 | — | — | EP | disclosed |
| US-11691956-B2 | Bio-based diols from sustainable raw materials, uses thereof to make diglycidyl ethers, and their coatings | NDSU RESEARCH FOUNDATION (US) | 2023-07-04 | — | — | US | disclosed |
| US-20230150942-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-05-18 | — | — | US | disclosed |
| US-11560356-B2 | Compounds and compositions for the treatment of cancer | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-01-24 | — | — | US | disclosed |
| CN-109661229-B | Compounds and compositions for the treatment of cancer | 加利福尼亚大学董事会 | 2022-06-28 | — | — | CN | disclosed |
| EP-3478284-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CANCER | The Regents of The University of California (US) | 2019-05-08 | — | — | EP | disclosed |
| CN-109661229-A | Compound and composition for treating cancer | 加利福尼亚大学董事会 | 2019-04-19 | — | — | CN | disclosed |
| EP-3071578-B1 | TRICYCLIC PIPERIDINE COMPOUNDS | ACTELION PHARMACEUTICALS LTD (CH) | 2018-01-10 | — | — | EP | disclosed |
| WO-2018005678-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-01-04 | — | — | WO | disclosed |
| US-9765092-B2 | Tricyclic piperidine compounds | ACTELION PHARMACEUTICALS LTD (CH) | 2017-09-19 | — | — | US | disclosed |
| US-20160272655-A1 | TRICYCLIC PIPERIDINE COMPOUNDS | ACTELION PHARMACEUTICALS LTD (CH) | 2016-09-22 | — | — | US | disclosed |
| US-7619092-B2 | Piperidine compounds | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-11-17 | — | — | US | disclosed |
| US-7619092-B2 | Piperidine compounds | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150942-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CANCER | TP53, HCCS, CFTR | CSF1R 4168/4885HDAC4 222/4885HDAC1 103/4885 |
| US-11560356-B2 | Compounds and compositions for the treatment of cancer | TP53, HCCS, CFTR | CSF1R 4168/4885HDAC4 222/4885HDAC1 103/4885 |
| US-20220000832-A1 | Pharmaceutical Composition for Preventing Greying of Hair and Preventing or Treating Poliosis or Vitiligo | TYR, MC1R, SDHB | CSF1R 3161/4885HDAC4 2887/4885HDAC1 1502/4885 |
| US-20160272655-A1 | TRICYCLIC PIPERIDINE COMPOUNDS | TPH1, HTR1B, HTR1A | CSF1R 1709/4885HDAC4 996/4885HDAC1 202/4885 |
| US-12227482-B2 | Compounds and compositions for the treatment of cancer | TP53, HCCS, CFTR | CSF1R 4168/4885HDAC4 222/4885HDAC1 103/4885 |
| US-11691956-B2 | Bio-based diols from sustainable raw materials, uses thereof to make diglycidyl ethers, and their coatings | DAD1, ESD, FTO | CSF1R 1892/4885HDAC4 2507/4885HDAC1 3409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.