Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13162795 | 0.81 | LRRK2 (0.32) | LRRK2CREBBPCHRM4 | |
| SCHEMBL15888552 | 0.75 | NLRP3 (0.40) | CREBBPCNR2CHRM4 | |
| SCHEMBL13634273 | 0.74 | RIPK1 (0.34) | LRRK2CREBBPCNR2CHRM4 | |
| SCHEMBL13638966 | 0.74 | MAP3K12 (0.32) | — | |
| SCHEMBL13634338 | 0.72 | OGA (0.41) | — | |
| SCHEMBL13634304 | 0.72 | HRH4 (0.38) | — | |
| SCHEMBL13612636 | 0.71 | HTR6 (0.44) | — | |
| SCHEMBL13634370 | 0.71 | MAPK1 (0.39) | — | |
| SCHEMBL13634211 | 0.70 | HRH4 (0.39) | LRRK2CHRM4 | |
| SCHEMBL13634313 | 0.69 | CNR2 (0.37) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |