Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PRKDC | P78527 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 3/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29387108 | 1.00 | ALDH1A1 (0.50) | ALDH1A1KDM4EGAAPRKDCLMNA | |
| SCHEMBL31540801 | 0.82 | SRC (0.47) | ALDH1A1KDM4EGAAPRKDCLMNA | |
| SCHEMBL135760 | 0.82 | SRC (0.47) | ALDH1A1KDM4EGAAPRKDCLMNA | |
| SCHEMBL2888296 | 0.78 | ERN1 (0.52) | ALDH1A1KDM4EGAALMNASMN1; SMN2 | |
| SCHEMBL2691345 | 0.78 | CYP2A6 (0.48) | ALDH1A1KDM4EGAAPRKDCLMNA | |
| SCHEMBL18814757 | 0.77 | ALDH1A1 (0.46) | ALDH1A1KDM4EGAALMNASRC | |
| SCHEMBL21240056 | 0.77 | NQO2 (0.35) | ALDH1A1KDM4EMAPTSMN1; SMN2HPGD | |
| SCHEMBL2141046 | 0.77 | TDP1 (0.40) | ALDH1A1KDM4EMAPTSMN1; SMN2HPGD | |
| SCHEMBL1162125 | 0.76 | ERN1 (0.56) | ALDH1A1PRKDCLMNAL3MBTL1ERN1 | |
| SCHEMBL29437223 | 0.76 | ALDH1A1 (0.52) | ALDH1A1KDM4EGAALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 250 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120117974-A | Synthetic method for preparing di-deuterated primary alcohol by catalytic aldehyde hydrogenation and hydrogen-deuterium exchange reaction | 中国科学院大连化学物理研究所 | 2025-06-10 | — | — | CN | claimed |
| CN-118026796-A | Synthetic method for decarbonylation deuteration reaction of rhodium-catalyzed aldehyde compound | 中国科学院大连化学物理研究所 | 2024-05-14 | — | — | CN | claimed |
| CN-110372722-B | Method for synthesizing sulfur-nitrogen-containing bis-heterocyclic compound | 河南师范大学 | 2020-08-11 | — | — | CN | claimed |
| US-20260125346-A1 | Isoquinolinone Derivatives and 4H-Quinolizinone Derivatives and Pharmaceutical Compositions Thereof for the Treatment of Disease | BEONE MEDICINES I GMBH (CH) | 2026-05-07 | — | — | US | disclosed |
| EP-4709711-A1 | ISOQUINOLINONE DERIVATIVES AND 4H-QUINOLIZINONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASE | Beone Medicines I GmbH (CH) | 2026-03-18 | — | — | EP | disclosed |
| EP-3565808-B1 | COMPOUNDS USEFUL FOR TREATING GASTROINTESTINAL TRACT DISORDERS | ARDELYX INC (US) | 2026-03-04 | — | — | EP | disclosed |
| US-12565497-B2 | Sulfone derivatives | HOFFMANN-LA ROCHE INC. (US) | 2026-03-03 | — | — | US | disclosed |
| EP-3573972-B1 | RORGAMMA MODULATORS AND USES THEREOF | GENFIT (FR) | 2026-01-14 | — | — | EP | disclosed |
| US-12391695-B2 | PRMT5 inhibitors | LUPIN LIMITED (IN) | 2025-08-19 | — | — | US | disclosed |
| US-20250250230-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2025-08-07 | — | — | US | disclosed |
| US-20250195483-A1 | SPIRO PIPERIDINE DERIVATIVES AS INHIBITORS OF APOL1 AND METHODS OF USING SAME | VERTEX PHARMA (US) | 2025-06-19 | — | — | US | disclosed |
| CN-1933826-A | Novel pharmaceutical compositions comprising agonists of the thyroid receptor | KAROBIO AB (SE) | 2007-03-21 | — | — | CN | disclosed |
| WO-2006136309-A1 | CRIPOWELLINS AND SYNTHETIC DERIVATIVES THEREOF USED AS MEDICAMENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2006-12-28 | — | — | WO | disclosed |
| EP-1278746-A2 | DIHYDROPYRIDINE COMPOUNDS AND METHODS OF USE | Abbott Laboratories (US) | 2003-01-29 | — | — | EP | disclosed |
| WO-2001083480-A2 | DIHYDROPYRIDINE COMPOUNDS AND METHODS OF USE | ABBOTT LABORATORIES (US) | 2001-11-08 | — | — | WO | disclosed |
| EP-0691973-A1 | THIENO-INDOLE DERIVATIVES AS 5HT2c AND 5HT2b ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1996-01-17 | — | — | EP | disclosed |
| WO-1994022871-A1 | THIENO-INDOLE DERIVATIVES AS 5HT2c AND 5HT2b ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-10-13 | — | — | WO | disclosed |
| US-4847438-A | INSECTICIDES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1989-07-11 | — | — | US | disclosed |
| US-4668701-A | Pesticides | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1987-05-26 | — | — | US | disclosed |
| EP-0104432-A2 | Herbicide and plant growth regulator comprising alpha-beta-unsaturated compound | TEIJIN LIMITED (JP) | 1984-04-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250250230-A1 | HETEROCYCLIC COMPOUND | HCRTR2, HCRTR1, NPY2R | ALDH1A1 976/4885KDM4E 1217/4885GAA 2452/4885 |
| US-12391695-B2 | PRMT5 inhibitors | PRMT5, PRMT1, PRMT3 | ALDH1A1 3123/4885KDM4E 142/4885GAA 885/4885 |
| US-20250195483-A1 | SPIRO PIPERIDINE DERIVATIVES AS INHIBITORS OF APOL1 AND METHODS OF USING SAME | APOL1, PNLIP, SAAL1 | ALDH1A1 1983/4885KDM4E 4713/4885GAA 2342/4885 |
| US-20260125346-A1 | Isoquinolinone Derivatives and 4H-Quinolizinone Derivatives and Pharmaceutical Compositions Thereof for the Treatment of Disease | NR3C1, NR3C2, PIK3R4 | ALDH1A1 1598/4885KDM4E 3237/4885GAA 1003/4885 |
| US-12565497-B2 | Sulfone derivatives | CXCR1, CCR1, SULT1E1 | ALDH1A1 1332/4885KDM4E 3565/4885GAA 2525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.