Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 2/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.56 |
| ▸ | REN | P00797 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.50 |
| ▸ | CTSS | P25774 | 2/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | YAP1 | P46937 | 2/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16387557 | 1.00 | BCL2 (0.58) | BCL2PTPN1RENPPARAHDAC8 | |
| SCHEMBL13571647 | 0.88 | PTPN1 (0.62) | BCL2PTPN1RENPPARAHDAC8 | |
| SCHEMBL13571645 | 0.88 | PTPN1 (0.62) | BCL2PTPN1RENPPARAHDAC8 | |
| SCHEMBL13570804 | 0.88 | PTPN1 (0.62) | BCL2PTPN1RENPPARAHDAC8 | |
| SCHEMBL13639719 | 0.87 | BCL2 (0.47) | BCL2PTPN1RENPPARACTSS | |
| SCHEMBL16343366 | 0.86 | LTA4H (0.47) | BCL2PTPN1PPARAYAP1LTA4H | |
| SCHEMBL16343367 | 0.86 | LTA4H (0.47) | BCL2PTPN1PPARAYAP1LTA4H | |
| SCHEMBL16387549 | 0.85 | ITGB3 (0.52) | BCL2PTPN1HDAC8ITGB3ITGA2B | |
| SCHEMBL3350988 | 0.85 | BCL2 (0.64) | BCL2PTPN1RENPPARAHDAC8 | |
| SCHEMBL6161729 | 0.85 | BCL2 (0.64) | BCL2PTPN1RENPPARAHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9238631-B2 | Radiolabeled amino acids for diagnostic imaging | PIRAMAL IMAGING SA (CH) | 2016-01-19 | — | — | US | disclosed |
| US-9238631-B2 | Radiolabeled amino acids for diagnostic imaging | PIRAMAL IMAGING SA (CH) | 2016-01-19 | — | — | US | disclosed |
| US-20150011773-A1 | RADIOLABELED AMINO ACIDS FOR DIAGNOSTIC IMAGING | PIRAMAL IMAGING SA (CH) | 2015-01-08 | — | — | US | disclosed |
| US-20150011773-A1 | RADIOLABELED AMINO ACIDS FOR DIAGNOSTIC IMAGING | PIRAMAL IMAGING SA (CH) | 2015-01-08 | — | — | US | disclosed |
| US-20130034497-A1 | IODINE-LABELED HOMOGLUTAMIC ACID AND GLUTAMIC ACID DERIVATIVES | PIRAMAL IMAGING SA (CH) | 2013-02-07 | — | — | US | disclosed |
| US-20130034497-A1 | IODINE-LABELED HOMOGLUTAMIC ACID AND GLUTAMIC ACID DERIVATIVES | PIRAMAL IMAGING SA (CH) | 2013-02-07 | — | — | US | disclosed |
| EP-2520556-A1 | Radiolabeled amino acids for diagnostic imaging | Bayer Pharma Aktiengesellschaft (DE) | 2012-11-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150011773-A1 | RADIOLABELED AMINO ACIDS FOR DIAGNOSTIC IMAGING | SLC1A5, SLC6A19, BCAT2 | BCL2 4876/4885PTPN1 4784/4885REN 1905/4885 |
| US-20130034497-A1 | IODINE-LABELED HOMOGLUTAMIC ACID AND GLUTAMIC ACID DERIVATIVES | GLUL, GCG, GLS | BCL2 4530/4885PTPN1 4634/4885REN 1258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.