SCHEMBL13640458

SCHEMBL13640458

CC1(C)CC(=O)C(=CNc2cccc(Cl)c2)C(=O)C1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 3/20 0.46
▸ KMT2A Q03164 3/20 0.46
▸ ALDH1A1 P00352 8/20 0.45
▸ CYP1A2 P05177 2/20 0.45
▸ CYP3A4 P08684 2/20 0.45
▸ RAB9A P51151 2/20 0.44
▸ LMNA P02545 2/20 0.44
▸ MAPT P10636 2/20 0.44
▸ NPC1 O15118 1/20 0.44
▸ BUB1 O43683 1/20 0.44
▸ MAPK1 P28482 1/20 0.43
▸ HSD17B10 Q99714 1/20 0.43
▸ CYP11B2 P19099 1/20 0.42
▸ CA4 P22748 1/20 0.42
▸ NPSR1 Q6W5P4 1/20 0.41
▸ GAA P10253 1/20 0.40
▸ KDM4E B2RXH2 1/20 0.39
▸ HTT P42858 2/20 0.38
▸ PGR P06401 1/20 0.38
▸ HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13640157 0.85 CYP11B2 (0.40) MEN1KMT2AALDH1A1CYP1A2CYP3A4
SCHEMBL13640143 0.84 ALDH1A1 (0.46) MEN1KMT2AALDH1A1CYP1A2CYP3A4
SCHEMBL22057718 0.82 MAOA (0.45) MEN1KMT2AALDH1A1RAB9AMAPT
SCHEMBL11109819 0.82 ALDH1A1 (0.60) KMT2AALDH1A1CYP1A2CYP3A4RAB9A
SCHEMBL18870869 0.81 KDM4E (0.47) MEN1KMT2AALDH1A1CYP1A2CYP3A4
SCHEMBL13640167 0.81 KMT2A (0.54) MEN1KMT2AALDH1A1RAB9ALMNA
SCHEMBL12830164 0.81 ALDH1A1 (0.67) MEN1KMT2AALDH1A1CYP1A2CYP3A4
SCHEMBL16704314 0.81 BUB1 (0.46) MEN1KMT2AALDH1A1CYP1A2CYP3A4
SCHEMBL13640183 0.80 MAPT (0.51) MEN1KMT2AALDH1A1CYP1A2CYP3A4
SCHEMBL13640140 0.79 PKM (0.46) MEN1KMT2AALDH1A1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2477491-B1 PLANT ADDITIVES AND USES THEREOF TO MODULATE THE SYNTHESIS OF MEMBRANE GLYCEROLIPIDS IN PLANTS COMMISSARIAT L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2017-05-17 — — EP disclosed
US-9028855-B2 Plant additives and uses thereof to modulate the synthesis of membrane glycerolipids in planta COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2015-05-12 — — US disclosed
US-9028855-B2 Plant additives and uses thereof to modulate the synthesis of membrane glycerolipids in planta COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2015-05-12 — — US disclosed
US-20120283101-A1 Plant Additives and Uses Thereof to Modulate the Synthesis of Membrane Glycerolipids in Planta COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2012-11-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120283101-A1 Plant Additives and Uses Thereof to Modulate the Synthesis of Membrane Glycerolipids in Planta PGM2, SGMS2, PHOSPHO1 MEN1 2145/4885KMT2A 1828/4885ALDH1A1 3248/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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